Rickets
MONDO:0005520Bone softening and weakening usually caused by deficiency or impaired metabolism of vitamin D. Deficiency of calcium, magnesium, or phosphorus may also cause rickets. It predominantly affects children who suffer from severe malnutrition. It manifests with bone pain, fractures, muscle weakness, and skeletal deformities.
Also known as: rachitis, rickets, rickets (disease), vitamin D hydroxylation-deficient rickets, active rickets, hypovitaminosis D, nutritional rickets, vitamin D deficiency disease
41 clinical trials for this condition and its sub-types, 10 tagged with Rickets itself.
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Sub-types of Rickets
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Hypophosphatemic rickets 3 trials · 19 incl. sub-types
1 sub-type
- Hereditary hypophosphatemic rickets 1 trial · 18 incl. sub-types Sub-types →
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Renal osteodystrophy 12 trials
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Hypocalcemic rickets 0 trials · 3 incl. sub-types
2 sub-types
- Vitamin D-dependent rickets, type 1 0 trials · 3 incl. sub-types Sub-types →
- Vitamin D-dependent rickets, type 2 0 trials Sub-types →
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Vitamin D-dependent rickets 0 trials · 3 incl. sub-types
3 sub-types
- Vitamin D-dependent rickets, type 1 0 trials · 3 incl. sub-types Sub-types →
- Vitamin D-dependent rickets, type 2 0 trials Sub-types →
- Vitamin D-dependent rickets, type 3 0 trials
Most studied deeper sub-types
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Which vitamin d pill is best for your bones? new study aims to find out.
Disease control Recruiting nowThis study looks at three different ways to take vitamin D in people with low levels. Participants will be randomly assigned to one of three groups: a monthly pill, a twice-monthly pill, or daily drops. After one month, researchers will measure vitamin D in the blood and check bo…
Sponsor: Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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Phosphate therapy's hidden toll on aging bodies revealed
Knowledge-focused Recruiting nowThis study looks at how long-term phosphate therapy affects the kidneys, blood vessels, and heart in people with two rare bone disorders: X-linked hypophosphatemia (XLH) and hereditary hypophosphatemic rickets with hypercalciuria (HHRH). Researchers will measure hormone levels an…
Early phase 1 • Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Could a lower dose of burosumab work just as well for XLH?
Knowledge-focused Recruiting nowXLH is a rare genetic condition that causes low phosphate levels, leading to weak bones and pain. Burosumab is a standard treatment, but the best starting dose is still unclear. This study will review the medical records of 120 children across England to see if a lower dose (unde…
Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Vitamin d registry launches to uncover hidden health trends
Knowledge-focused Recruiting nowThis study will follow 1,000 adults who are taking vitamin D supplements for low vitamin D levels. Researchers will collect health data over 10 years to see how vitamin D use relates to conditions like heart disease, diabetes, cancer, and osteoporosis. The goal is to learn more a…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Can vitamins d and k boost your gut bacteria? new study investigates
Knowledge-focused Recruiting nowThis study looks at how taking vitamin D3 and K2 supplements for 90 days changes blood levels and the community of bacteria in the gut (the microbiome) in healthcare workers with low vitamin D. About 96 participants will take either a vitamin D3, K2, both, or a placebo pill. Rese…
Sponsor: Madigan Army Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Could vitamin d and weight predict fractures in kids?
Knowledge-focused Recruiting nowThis study is looking at 100 children aged 3 to 15 who have had a low-energy fracture (like a fall from standing height). Researchers want to see if vitamin D levels, bone markers, and weight are linked to fracture risk. They will compare children with fractures to those without.…
Sponsor: Paracelsus Medical University • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:54 UTC