RHO-related retinopathy
MONDO:0700380Any retinopathy caused by a variant in the RHO gene, including cases diagnosed as congenital stationary night blindness autosomal dominant 1 or retinitis pigmentosa 4.
Also known as: RHO-related retinopathy
39 clinical trials for this condition and its sub-types.
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Broader categories
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New pill could slow blindness in inherited eye disease
Disease control OngoingThis early-stage trial tests a new oral drug called OCT-980 for people with a specific inherited eye disease (autosomal dominant retinitis pigmentosa) that causes gradual vision loss and blindness. The study first gives a single dose to healthy volunteers to check safety, then mu…
Phase: PHASE1, PHASE2 • Sponsor: Octant, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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Gene therapy trial aims to restore night vision in rare eye disease
Disease control OngoingThis study tests a gene therapy called OCU400 for people with retinitis pigmentosa, an inherited eye disease that causes vision loss. The treatment is injected under the retina to help light-sensitive cells work better. The trial enrolled 140 people aged 3 and older and measures …
Phase: PHASE3 • Sponsor: Ocugen • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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New eye tests could speed up retinitis pigmentosa treatment trials
Knowledge-focused OngoingThis study aims to find better ways to measure how retinitis pigmentosa (a genetic eye disease that causes vision loss) progresses over time. Researchers will use advanced imaging and vision tests in 40 people with specific genetic forms of the disease. The goal is to identify re…
Sponsor: University Hospital Tuebingen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Free eye tests aim to catch vision loss early in harlem and washington heights
Knowledge-focused OngoingThis study offers free vision screenings to underserved adults over 40 living in affordable housing in Harlem and Washington Heights. The goal is to find eye problems like glaucoma, cataracts, and diabetic retinopathy early and connect people with follow-up care. About 749 partic…
Phase: NA • Sponsor: Columbia University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC