Retinitis pigmentosa
MONDO:0019200Retinitis pigmentosa (RP) is an inherited retinal dystrophy leading to progressive loss of the photoreceptors and retinal pigment epithelium and resulting in blindness usually after several decades.
Also known as: retinitis pigmentosa, pericentral pigmentary retinopathy, Rod-cone dystrophy
107 clinical trials for this condition and its sub-types, 84 tagged with Retinitis pigmentosa itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Retinitis pigmentosa
-
Retinitis pigmentosa 3 7 trials
-
Retinitis pigmentosa 4 5 trials
-
Retinitis pigmentosa 11 4 trials
-
Retinitis pigmentosa 39 3 trials
-
Retinitis pigmentosa 1 1 trial
-
Retinitis pigmentosa 25 1 trial
-
Retinitis pigmentosa 37 1 trial
-
Retinitis pigmentosa 40 1 trial
-
Retinitis pigmentosa 45 1 trial
-
Retinitis pigmentosa 47 1 trial
-
Retinitis pigmentosa Y-linked 1 trial
-
Cone-rod dystrophy 15 0 trials
-
Cone-rod dystrophy 16 0 trials
-
Cone-rod dystrophy 2 0 trials
-
Retinal dystrophy and obesity 0 trials
-
Retinitis pigmentosa 10 0 trials
-
Retinitis pigmentosa 100 0 trials
-
Retinitis pigmentosa 12 0 trials
-
Retinitis pigmentosa 13 0 trials
-
Retinitis pigmentosa 14 0 trials
-
Retinitis pigmentosa 17 0 trials
-
Retinitis pigmentosa 18 0 trials
-
Retinitis pigmentosa 19 0 trials
-
Retinitis pigmentosa 2 0 trials
-
Retinitis pigmentosa 20 0 trials
-
Retinitis pigmentosa 22 0 trials
-
Retinitis pigmentosa 23 0 trials
-
Retinitis pigmentosa 24 0 trials
-
Retinitis pigmentosa 26 0 trials
-
Retinitis pigmentosa 27 0 trials
-
Retinitis pigmentosa 28 0 trials
-
Retinitis pigmentosa 29 0 trials
-
Retinitis pigmentosa 30 0 trials
-
Retinitis pigmentosa 31 0 trials
-
Retinitis pigmentosa 32 0 trials
-
Retinitis pigmentosa 33 0 trials
-
Retinitis pigmentosa 34 0 trials
-
Retinitis pigmentosa 35 0 trials
-
Retinitis pigmentosa 36 0 trials
-
Retinitis pigmentosa 38 0 trials
-
Retinitis pigmentosa 41 0 trials
-
Retinitis pigmentosa 42 0 trials
-
Retinitis pigmentosa 43 0 trials
-
Retinitis pigmentosa 44 0 trials
-
Retinitis pigmentosa 46 0 trials
-
Retinitis pigmentosa 48 0 trials
-
Retinitis pigmentosa 49 0 trials
-
Retinitis pigmentosa 50 0 trials
-
Retinitis pigmentosa 51 0 trials
-
Retinitis pigmentosa 53 0 trials
-
Retinitis pigmentosa 54 0 trials
-
Retinitis pigmentosa 55 0 trials
-
Retinitis pigmentosa 56 0 trials
-
Retinitis pigmentosa 57 0 trials
-
Retinitis pigmentosa 58 0 trials
-
Retinitis pigmentosa 59 0 trials
-
Retinitis pigmentosa 6 0 trials
-
Retinitis pigmentosa 60 0 trials
-
Retinitis pigmentosa 61 0 trials
-
Retinitis pigmentosa 62 0 trials
-
Retinitis pigmentosa 63 0 trials
-
Retinitis pigmentosa 64 0 trials
-
Retinitis pigmentosa 65 0 trials
-
Retinitis pigmentosa 66 0 trials
-
Retinitis pigmentosa 67 0 trials
-
Retinitis pigmentosa 68 0 trials
-
Retinitis pigmentosa 69 0 trials
-
Retinitis pigmentosa 7 0 trials
-
Retinitis pigmentosa 7, digenic 0 trials
-
Retinitis pigmentosa 70 0 trials
-
Retinitis pigmentosa 71 0 trials
-
Retinitis pigmentosa 72 0 trials
-
Retinitis pigmentosa 73 0 trials
-
Retinitis pigmentosa 74 0 trials
-
Retinitis pigmentosa 75 0 trials
-
Retinitis pigmentosa 76 0 trials
-
Retinitis pigmentosa 77 0 trials
-
Retinitis pigmentosa 78 0 trials
-
Retinitis pigmentosa 79 0 trials
-
Retinitis pigmentosa 80 0 trials
-
Retinitis pigmentosa 81 0 trials
-
Retinitis pigmentosa 83 0 trials
-
Retinitis pigmentosa 84 0 trials
-
Retinitis pigmentosa 85 0 trials
-
Retinitis pigmentosa 86 0 trials
-
Retinitis pigmentosa 88 0 trials
-
Retinitis pigmentosa 9 0 trials
-
Retinitis pigmentosa 90 0 trials
-
Retinitis pigmentosa 92 0 trials
-
Retinitis pigmentosa 93 0 trials
-
Retinitis pigmentosa 95 0 trials
-
Retinitis pigmentosa 96 0 trials
-
Retinitis pigmentosa 97 0 trials
-
Retinitis pigmentosa 98 0 trials
-
Retinitis pigmentosa 99 0 trials
-
Can an eye injection slow a genetic cause of blindness?
Disease control Not yet recruitingThis trial tests the long-term safety of an experimental medicine called ultevursen, given as an injection into the eye, for people with retinitis pigmentosa caused by mutations in a gene called USH2A. The study enrolls about 81 adults and children who completed a previous 24-mon…
Phase 2 • Sponsor: Laboratoires Thea • Aim: Disease control
Last updated Sep 03, 2026 00:00 UTC
-
Can a statin nanoparticle save sight in retinitis pigmentosa?
Disease control Not yet recruitingThis phase 1 trial tests whether an intravenous nanoparticle formulation of pitavastatin, called ULREA-PVS-NP, is safe in adults with retinitis pigmentosa, a rare inherited disease that causes progressive vision loss. The study aims to see if the treatment can reduce retinal infl…
Phase 1 • Sponsor: Kyushu University • Aim: Disease control
Last updated Aug 21, 2026 00:00 UTC
-
Can an antioxidant pill slow blindness in usher syndrome?
Disease control Not yet recruitingThis phase 3 trial tests whether an experimental drug called NPI-001 can slow the loss of light-sensing cells in the eyes of adults with Usher syndrome, a genetic condition that causes both hearing and vision loss. About 80 participants take either NPI-001 or a placebo twice dail…
Phase 3 • Sponsor: Nacuity Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jul 19, 2026 00:00 UTC
-
New drug aims to preserve sight in rare genetic blindness
Disease control Not yet recruitingThis phase 3 trial tests whether NPI-001, taken twice daily for 24 months, can slow the loss of light-sensing cells in the eyes of adults with Usher syndrome, a genetic condition that causes both hearing and vision loss. About 80 participants will receive either the drug or a pla…
Phase 3 • Sponsor: Nacuity Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jul 03, 2026 00:00 UTC
-
Gene therapy injection aims to save sight in rare eye disease
Disease control Not yet recruitingThis early-stage trial tests a single injection of ZM-02, a gene therapy, in 21 people aged 6 to 60 with advanced retinitis pigmentosa, a genetic condition that causes progressive vision loss. Participants are randomly assigned to receive either a low or high dose of ZM-02 or a s…
Phase 1/2 • Sponsor: Zhongmou Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
-
Stem cell therapy for rare eye disease passes 5-year safety check
Disease control Not yet recruitingThis study follows up 18 people who received umbilical cord stem cells or conditioned medium for retinitis pigmentosa, a rare eye disease that causes vision loss. Researchers will check vision, eye structure, and safety five years after the injection. The goal is to see if the tr…
Sponsor: PT. Prodia Stem Cell Indonesia • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
-
Could stem cells save sight? new trial tests umbilical cord therapy for eye disease
Disease control Not yet recruitingThis study tests whether stem cells from umbilical cord tissue can safely slow vision loss in people with retinitis pigmentosa, an inherited eye disease. Thirty participants will receive one of two doses injected around the eye and be monitored for six months. The main goals are …
Phase 2/3 • Sponsor: PT. Prodia Stem Cell Indonesia • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
-
Gene therapy injection aims to slow vision loss in rare eye disease
Disease control Not yet recruitingThis early-stage trial tests a single injection of a gene therapy drug called UGX202 in 6 adults with advanced retinitis pigmentosa, a genetic condition that causes vision loss. The main goal is to check if the treatment is safe and tolerable over 52 weeks. Researchers will also …
Early phase 1 • Sponsor: Suzhou UgeneX Therapeutics Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
-
Could pond scum help teens see better? new trial tests alga extract for rare eye disease
Disease control Not yet recruitingThis study tests whether a powder made from a special alga can help preserve or improve vision in teenagers with retinitis pigmentosa, a genetic eye disease that causes vision loss. Thirty participants aged 12-18 will take the alga extract daily for one year. The study will measu…
Phase 1/2 • Sponsor: Sheba Medical Center • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
-
New eye scanner could spot hidden signs of blindness
Diagnosis Not yet recruitingThis study will test a new, non-invasive eye scanner called wide field OCTA in 200 people with various eye diseases, including age-related macular degeneration, diabetic retinopathy, and dry eye. The goal is to see if this device can provide better images of blood vessels in the …
Sponsor: IRCCS San Raffaele • Aim: Diagnosis
Last updated Jun 27, 2026 08:07 UTC
-
Sound waves to restore sight? new ultrasound trial for AMD and RP patients
Symptom relief Not yet recruitingThis early study tests whether a wearable ultrasound device can safely stimulate retinal cells and help restore vision in people with age-related macular degeneration or retinitis pigmentosa. Five participants will receive short ultrasound pulses while reporting what they see. Th…
Sponsor: University of Southern California • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
-
A sharper look at the retina: new imaging technology may spot eye disease earlier
Knowledge-focused Not yet recruitingThis study is testing whether a specialized eye scanner called the MONA IV can capture clear, detailed images of the retina's tiny cells and blood vessels. Researchers will use it in people with conditions like glaucoma or age-related macular degeneration, as well as in healthy v…
Sponsor: Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts • Aim: Knowledge-focused
Last updated Jul 26, 2026 00:00 UTC
-
Scientists track eye disease patterns to speed future cures
Knowledge-focused Not yet recruitingThis study looks back at medical records of 200 people with inherited retinal diseases, like retinitis pigmentosa and Stargardt disease. Researchers will analyze vision tests and eye scans to see how these diseases progress and how genetics affect symptoms. The goal is to find be…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC