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Primary orthostatic tremor

MONDO:0016546

Primary orthostatic tremor (POT), or ``shaky legs syndrome'', is a rare movement disorder characterized by fast, task-specific tremor, affecting the legs and trunk while standing.

Also known as: POT, pot, OT, orthostatic tremor, primary, shaky leg syndrome

15 clinical trials for this condition and its sub-types.

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Broader categories

Disease (618) Nervous system disorder (217) Movement disorder (89) Human disease (14) Disease by body system or component (0)
Trials to join now! 10 Not yet finished but already full! 1 Completed 4
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  • Sound waves aim to quiet shaky legs in rare tremor disorder

    Symptom relief Ongoing

    This study tests whether low-intensity focused ultrasound (LIFUS) can calm abnormal brain activity in the cerebellum that causes severe leg tremors when standing. Fifteen adults with primary orthostatic tremor will receive real or sham ultrasound while their tremor and brain circ…

    Phase: NA • Sponsor: University Health Network, Toronto • Aim: Symptom relief

    Last updated Jun 27, 2026 09:08 UTC

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