Sound waves calm shaky legs: new hope for rare tremor disorder

NCT ID NCT05547620

First seen Feb 25, 2026 · Last updated May 15, 2026 · Updated 17 times

Summary

This study tests a new, non-invasive treatment for primary orthostatic tremor, a rare condition that causes leg shaking and a feeling of falling when standing. The treatment uses low-intensity focused ultrasound to calm overactive brain circuits in the cerebellum. Researchers will compare real ultrasound to a sham (fake) treatment in 15 adults to see if it reduces tremor and improves standing stability.

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Contacts and locations

Locations

  • Toronto Western Hospital

    Toronto, Ontario, M5T 2S8, Canada

Conditions

Explore the condition pages connected to this study.