Primary hyperparathyroidism
MONDO:0010837Hyperfunction of the parathyroid glands resulting in the overproduction of parathyroid hormone. It is caused by parathyroid adenoma, parathyroid hyperplasia, parathyroid carcinoma, and multiple endocrine neoplasia. It is associated with hypercalcemia and hypophosphatemia. Signs and symptoms include weakness, fatigue, nausea, vomiting, constipation, depression, bone pain, osteoporosis, cystic bone lesions, and kidney stones.
Also known as: primary hyperparathyroidism, primary hyperparathyroidism (disease)
55 clinical trials for this condition and its sub-types.
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Broader categories
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New study could change how Men's UTIs are treated
Disease control Not yet recruitingThis study tests whether a common antibiotic for women's UTIs, fosfomycin-trometamol, works well for men with urinary tract infections. Current treatments can have serious side effects and increase antibiotic resistance. The trial will enroll 138 men in primary care and monitor f…
Phase: PHASE3 • Sponsor: University Hospital, Rouen • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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Parathyroid surgery may lower blood pressure hormone, study hopes to find out
Knowledge-focused Not yet recruitingThis study follows 400 adults with primary hyperparathyroidism who are scheduled for parathyroid surgery. Researchers will measure aldosterone, a hormone that helps control blood pressure, before surgery and at 3, 6, and 12 months after. They will also track blood pressure and us…
Sponsor: Central Hospital, Nancy, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC