Preneoplastic lesion
MONDO:1060215A precancerous condition characterized by accumulation of some molecular alterations necessary for malignant transformation in a clonal proliferation of cells, representing an intermediate stage in carcinogenesis with increased risk of progression to invasive neoplasia.
16 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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New robot could transform hysterectomy surgery
Disease control OngoingThis study is testing a new robotic system, the Medtronic Hugo™, for performing hysterectomies. It includes 70 patients with conditions like uterine fibroids, endometriosis, or certain cancers. The goal is to see if the robot is safe and can complete the surgery without switching…
Phase: NA • Sponsor: Medtronic - MITG • Aim: Disease control
Last updated Jun 27, 2026 13:01 UTC
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New camera tech could catch mouth cancer earlier
Diagnosis OngoingThis study tests whether special imaging devices can better detect pre-cancerous or cancerous spots in the mouth compared to a standard visual exam. About 63 adults with suspicious mouth lesions or a history of oral cancer will be followed over time. The goal is to see if these a…
Phase: EARLY_PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Diagnosis
Last updated Jun 27, 2026 12:08 UTC
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Glow-in-the-Dark mouth scans could catch cancer early
Diagnosis OngoingThis study tests whether special lights and cameras can help find early signs of mouth cancer in people at high risk. About 338 participants with precancerous spots or conditions like Fanconi anemia will have their mouths examined with fluorescence imaging, which makes abnormal c…
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Diagnosis
Last updated Jun 27, 2026 09:11 UTC
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Hunger training may help cut breast cancer risk in obese women
Prevention OngoingThis pilot study looks at whether adding hunger training to a standard diabetes prevention program helps obese women at high risk for breast cancer lose weight and lower their cancer risk. About 51 participants will learn weight-loss strategies and how to recognize true hunger. T…
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Prevention
Last updated Jun 27, 2026 12:07 UTC
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AI takes on esophageal cancer: could it spot the disease earlier?
Knowledge-focused ENROLLING_BY_INVITATIONThis study is testing whether an artificial intelligence (AI) model can help doctors better detect, diagnose, and treat esophageal cancer. Researchers will feed de-identified data from 12,000 patients receiving routine care into the AI and compare its recommendations to standard …
Sponsor: The First Affiliated Hospital of Henan University of Science and Technology • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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Cancer tissue bank study aims to unlock new treatment clues
Knowledge-focused ENROLLING_BY_INVITATIONThis study collects tissue and blood samples from 1,200 adults with known or suspected cancer. The samples are taken during standard surgeries or biopsies, with no extra procedures. Researchers will compare cancerous and normal tissues to identify differences that could lead to n…
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Hidden gene changes could reveal who gets cancer
Knowledge-focused OngoingThis study searches for new gene changes (mutations) that appear in cancer patients but not in their healthy parents. By comparing DNA from 1,275 people with certain cancers and their families, researchers hope to find genetic clues that increase cancer risk. The goal is to bette…
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC