Polymyalgia rheumatica
MONDO:0019735A syndrome characterized by pain, stiffness, and tenderness of the proximal muscle groups including the shoulder, pelvic girdle and the neck. There is no muscle atrophy and muscle biopsies do not reveal pathologic changes. Additional signs and symptoms include low grade fever, fatigue and depression.
Also known as: polymyalgia rheumatica, rhizomelic pseudopolyarthritis
29 clinical trials for this condition and its sub-types.
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New pill could replace steroids for painful muscle condition
Disease control Not yet recruitingThis study tests a drug called ivarmacitinib for people with polymyalgia rheumatica, a condition causing muscle pain and stiffness. The goal is to see if it can control the disease without needing steroids. About 80 adults aged 50-75 will take either the drug or a placebo, and re…
Phase: NA • Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC
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Could retraining movement ease the pain of polymyalgia rheumatica?
Symptom relief Not yet recruitingThis trial tests whether a personalized rehabilitation program called Movement Pattern Training can help people with polymyalgia rheumatica (PMR) reduce pain and improve their ability to do daily activities. The program includes motivational interviewing, activity-specific traini…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated Aug 08, 2026 00:03 UTC
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DNA clues could forecast steroid relapse in PMR
Knowledge-focused Not yet recruitingThis study investigates whether DNA methylation patterns in blood immune cells can predict which patients with Polymyalgia Rheumatica (PMR) will relapse when corticosteroid treatment is tapered. Researchers will analyze blood samples from 50 PMR patients to see if specific immune…
Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Knowledge-focused
Last updated Aug 14, 2026 00:00 UTC
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New study aims to unravel mysteries of common inflammatory condition in older adults
Knowledge-focused Not yet recruitingThis study will follow 400 people recently diagnosed with polymyalgia rheumatica, a condition causing shoulder and hip pain. Researchers will track symptoms, treatments, and outcomes over 5 years to better understand the disease and improve diagnosis. Participants will provide bl…
Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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Could arthritis and arteritis be connected? new study investigates
Knowledge-focused Not yet recruitingThis study aims to see if there is a connection between two types of inflammatory conditions: one affecting the spine and joints (spondylarthritis) and another affecting blood vessels (giant cell arteritis) or muscles (polymyalgia rheumatica). Researchers will compare 10 adults w…
Sponsor: Hôpital NOVO • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC