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POLD2-related combined immunodeficiency

MONDO:1010175

A non-severe combined immunodeficiency due to polymerase delta deficiency in which the cause of the disease is a variation in the POLD2 gene.

Also known as: Polymerase D2 deficiency, POLD2-related combined immunodeficiency

15 clinical trials for this condition and its sub-types.

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Broader categories

Disease (618) Hereditary disease (172) Immune system disorder (140) Immunodeficiency disease (48) Human disease (14) Combined immunodeficiency (3) Disease of genetic or genomic mechanism (2) Disease by body system or component (0) Disease by etiologic mechanism (0) Non-SCID combined immunodeficiency (0)
Trials to join now! 11 Completed 3 Terminated 1
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  • New stem cell method aims to protect kids with rare immune disease

    Disease control Terminated

    This study tested a way to improve stem cell transplants for children with combined immunodeficiency (CID), a condition where the immune system doesn't work properly. The approach removed certain naive cells from the donor stem cells to try to prevent graft-versus-host disease (a…

    Phase: PHASE2 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control

    Last updated Jun 27, 2026 12:02 UTC

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