Pleural mesothelioma
MONDO:0003308A neoplasm that arises from the mesothelial cells of the pleura. The primary cause is exposure to asbestos. The major histologic variants are the epithelioid malignant mesothelioma, desmoplastic malignant mesothelioma, and sarcomatoid malignant mesothelioma. Patients present with persistent cough and shortness of breath.
Also known as: mesothelioma of pleura, mesothelioma of the pleura, pleura mesothelioma, pleural mesothelioma, pleural mesothelioma (disease), benign pleural mesothelioma, pleural mesothelioma (disease), benign
1517 clinical trials for this condition and its sub-types, 28 tagged with Pleural mesothelioma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Pleural mesothelioma
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Malignant pleural mesothelioma 71 trials · 75 incl. sub-types
2 sub-types
- Pleural epithelioid mesothelioma 8 trials
- Pleural sarcomatoid mesothelioma 2 trials
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Pleural adenomatoid tumor 0 trials
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New drug XmAb20717 tested in rare cancers – trial suspended
Disease control PausedThis phase II trial tests the safety and effectiveness of a drug called XmAb20717 in 140 people with advanced rare cancers, including mesothelioma, lymphoma, and small cell lung cancer. The drug is given by IV. The main goal is to see if tumors shrink. The trial is currently susp…
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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Promising mesothelioma drug trial pulled before it even started
Disease control CancelledThis study was designed to test the drug alrizomadlin (APG-115) in people with BAP1 cancer syndrome who have early-stage mesothelioma that does not yet need standard treatment. The goal was to see if the drug could stabilize or improve the disease. However, the trial was withdraw…
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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New combo therapy for mesothelioma: radiation plus surgery under study
Disease control OngoingThis study is testing a new approach for people with malignant pleural mesothelioma, a rare lung cancer. It combines high-dose radiation (including a special boost to target bulky tumors) with surgery to remove the affected tissue. The main goal is to find the highest safe radiat…
Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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New combo therapy shows promise for rare lung cancer
Disease control OngoingThis study tests whether giving a combination of the immunotherapy drug pembrolizumab and chemotherapy before surgery can help people with a rare cancer called pleural mesothelioma. The trial involves 41 adults with early-stage disease that can be surgically removed. The main goa…
Phase 2 • Sponsor: Istituto Oncologico Veneto IRCCS • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC