Patent ductus arteriosus
MONDO:0011827A congenital defect characterized by the failure of the ductus arteriosus to close soon after birth. As a consequence, blood from the aorta mixes with blood from the pulmonary artery. If untreated, it may lead to congestive heart failure.
Also known as: PDA, patent ductus arteriosus, patent ductus botalli, persistent patency of the arterial duct, patency of the ductus arteriosus, patent ductus arteriosus familial (type)
102 clinical trials for this condition and its sub-types, 28 tagged with Patent ductus arteriosus itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Patent ductus arteriosus
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Char syndrome 0 trials
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PDA1 0 trials
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Patent ductus arteriosus 2 0 trials
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Patent ductus arteriosus 3 0 trials
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App-Based exercise program aims to strengthen hearts in congenital disease
Disease control Stopped earlyThis study tests a remote, app-enabled exercise program designed for people aged 10 to 50 with congenital heart disease. Participants use a smartphone app with exercise modules and wearable devices to track heart rate and progress. The goal is to see if this approach can safely i…
Sponsor: Duke University • Aim: Disease control
Last updated Aug 07, 2026 00:00 UTC
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Abandoned study: can a common painkiller help close a tiny heart vessel in preemies?
Disease control Stopped earlyThis study tested whether adding acetaminophen to standard ibuprofen treatment could better close a blood vessel (ductus arteriosus) that stays open too long in very premature infants. The trial was planned for preterm babies born at or before 27 weeks and 6 days who needed breat…
Phase 2 • Sponsor: University of South Alabama • Aim: Disease control
Last updated Jun 27, 2026 12:26 UTC