Pancoast syndrome
MONDO:0024674A rare neoplastic syndrome characterized by obstruction of the thoracic outlet leading to compression of the brachial plexus and vessels within. It is usually caused by a malignant neoplasm in the superior pulmonary sulcus. The most commonly involved neoplasms are non-small cell lung carcinomas. Clinical signs include Horner's syndrome, shoulder pain radiating down the arm in the ulnar distribution followed by edema and atrophy of the affected extremity. Clinical course usually leads to early local invasion of the bony thoracic structures. Prognosis is highly stage-dependent.
Also known as: Pancoast syndrome, Pancoast's syndrome, Pancoast tumor, Pancoast tumour, Pancoasts syndrome, superior pulmonary sulcus syndrome, syndrome, Pancoast, syndrome, Pancoast's
4 clinical trials for this condition and its sub-types.
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New combo therapy aims to shrink Hard-to-Treat lung tumors before surgery
Disease control OngoingThis phase 2 trial tests giving chemotherapy (carboplatin and paclitaxel) plus the immunotherapy drug nivolumab before surgery for people with Pancoast tumors, a rare type of lung cancer. After surgery, additional treatment is tailored based on whether the tumor was fully removed…
Phase: PHASE2 • Sponsor: Fundación GECP • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Virtual reality goggles could ease cancer Patients' procedure fears
Symptom relief OngoingThis study tests whether using a virtual reality headset during PICC line placement can reduce anxiety and pain in cancer patients. About 120 adults will be randomly assigned to either receive VR plus standard care or standard care alone. The goal is to see if this non-drug appro…
Phase: NA • Sponsor: Istituto Oncologico Veneto IRCCS • Aim: Symptom relief
Last updated Jun 27, 2026 12:30 UTC