Otosclerosis

MONDO:0005349

Formation of spongy bone in the labyrinth capsule which can progress toward the stapes (stapedial fixation) or anteriorly toward the cochlea leading to conductive, sensorineural, or mixed hearing loss. Several genes are associated with familial otosclerosis with varied clinical signs.

Also known as: otosclerosis, otosclerosis (disease)

6 clinical trials for this condition and its sub-types, 4 tagged with Otosclerosis itself.

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Where it sits in the disease tree

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Part of

↑ Inner ear disorder (149) ↑ Inherited auditory system disease (120) ↑ Hereditary otorhinolaryngologic disease (102)

Sub-types of Otosclerosis

Congenital corneal opacities, cornea guttata, and corectopia 0 trials
Otosclerosis 1 0 trials
Otosclerosis 10 0 trials
Otosclerosis 11 0 trials
Otosclerosis 12 0 trials
Otosclerosis 2 0 trials
Otosclerosis 3 0 trials
Otosclerosis 4 0 trials
Otosclerosis 5 0 trials
Otosclerosis 7 0 trials
Otosclerosis 8 0 trials

Including sub-types (6) Tagged with Otosclerosis (4)

Not yet recruiting 1 Not yet finished but already full! 1 Completed 2

New ear surgery aims to restore hearing without large incisions

Disease control Not yet recruiting

This study tests a surgical procedure called endoscopic stapedotomy for people with otosclerosis, a condition that causes progressive hearing loss. Surgeons will use a tiny camera to place a small artificial device in the middle ear to improve sound transmission. The study will f…

Sponsor: Sohag University • Aim: Disease control

Last updated Jun 27, 2026 08:06 UTC

Otosclerosis

Where it sits in the disease tree

New ear surgery aims to restore hearing without large incisions