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Oculocerebrorenal syndrome

MONDO:0010645

Oculocerebrorenal syndrome of Lowe (OCRL) is a multisystem disorder characterized by congenital cataracts, glaucoma, intellectual disabilities, postnatal growth retardation and renal tubular dysfunction with chronic renal failure.

Also known as: Lowe disease, Lowe oculo-cerebro-renal syndrome, Lowe oculocerebrorenal syndrome, Lowe syndrome, Lowe syndrome, X-linked recessive, OCR, OCRL, oculo-cerebro-renal dystrophy

4 clinical trials for this condition and its sub-types.

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Broader categories

Disease (680) Metabolic disease (233) Kidney disorder (214) Hereditary disease (176) Eye disorder (102) Urinary system disorder (66) Inborn errors of metabolism (45) Syndromic disease (25) Human disease (14) Inborn disorder of amino acid metabolism (4)
Trials to join now! 2 Not yet recruiting 1 Completed 1
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  • Promising drug aims to slow kidney damage in rare lowe syndrome

    Disease control Not yet recruiting

    This early study tests a drug called piclidenoson in 5 adult men with Lowe syndrome, a rare genetic disorder that harms the kidneys. The goal is to see if the drug can improve how the kidneys reabsorb important small proteins over 6 months. Researchers will also check safety and …

    Phase: PHASE2 • Sponsor: Can-Fite BioPharma • Aim: Disease control

    Last updated Jun 27, 2026 09:05 UTC

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