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Nondystrophic myotonia

MONDO:0054869

Also known as: NDM

4 clinical trials for this condition and its sub-types.

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Broader categories

Disease (717) Musculoskeletal system disorder (214) Muscle tissue disorder (56) Syndromic disease (25) Human disease (15) Myotonic syndrome (11) Skeletal muscle disorder (10) Disease by body system or component (0)
Trials to join now! 2 Not yet recruiting 1 Completed 1
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  • New study tests safer version of muscle stiffness drug

    Symptom relief Recruiting now

    This study tests a new extended-release form of mexiletine (mexiletine PR) against the standard immediate-release version in people with non-dystrophic myotonias, a group of rare genetic disorders that cause muscle stiffness. About 24 adults aged 16 and older will take each versi…

    Phase 3 • Sponsor: Lupin Ltd. • Aim: Symptom relief

    Last updated Jun 27, 2026 08:05 UTC

  • New registry tracks safety of mexiletine in kids with myotonia

    Symptom relief Recruiting now

    This study follows up to 10 children from birth to under 6 years old who have genetic muscle disorders causing stiffness (myotonia) and are taking mexiletine. Researchers will collect data on side effects and how the medicine is used in routine care over the long term. The goal i…

    Sponsor: Lupin Ltd. • Aim: Symptom relief

    Last updated Jun 27, 2026 07:51 UTC

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