Neurohypophyseal diabetes insipidus
MONDO:0007450Hereditary central diabetes insipidus is a rare genetic subtype of central diabetes insipidus (CDI) characterized by polyuria and polydipsia due to a deficiency in vasopressin (AVP) synthesis.
Also known as: ADH deficiency, AVP deficiency, Arginine vasopressin deficiency, antidiuretic hormone deficiency, diabetes insipidus of pituitary gland, hereditary CDI, hereditary neurogenic diabetes insipidus, pituitary gland diabetes insipidus
11 clinical trials for this condition and its sub-types.
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Sugar alcohol infusion may help diagnose thirst disorders
Diagnosis CompletedThis study tested whether infusing mannitol, a sugar alcohol, can help diagnose polyuria-polydipsia syndrome—a condition of excessive thirst and urination. Researchers measured copeptin levels in 42 healthy adults and patients after mannitol or placebo infusion. The goal was to s…
Phase: NA • Sponsor: University Hospital, Basel, Switzerland • Aim: Diagnosis
Last updated Jun 27, 2026 08:04 UTC
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Can estrogen boost the 'Love Hormone' in a rare condition?
Knowledge-focused CompletedThis pilot study tested whether a single dose of oral estrogen-progestin can raise oxytocin levels in people with arginine vasopressin deficiency (AVD), a rare condition that also causes low oxytocin. Researchers compared 28 adults—some with AVD and some healthy—to see if oxytoci…
Phase: EARLY_PHASE1 • Sponsor: Elizabeth Austen Lawson • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC