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Neoplasm of mature B-cells

MONDO:0004949

A neoplasm of follicle center B cells which has at least a partial follicular pattern. Follicular lymphomas comprise about 35% of adult non-Hodgkin lymphomas in the U.S. and 22% worldwide. Most patients have widespread disease at diagnosis. Morphologically, follicular lymphomas are classified as Grade 1, Grade 2, and Grade 3, depending on the percentage of the large lymphocytes present. The vast majority of cases (70-95%) express the BCL-2 rearrangement [t(14;18)]. Histological grade correlates with prognosis. Grades 1 and 2 follicular lymphomas are indolent and grade 3 is more aggressive (adapted from WHO, 2001).

Also known as: mature B-cell lymphocytic neoplasm, mature B-cell neoplasm, mature B-cell neoplasms

4517 clinical trials for this condition and its sub-types, 14 tagged with Neoplasm of mature B-cells itself.

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↑ B-cell neoplasm (3174)

Sub-types of Neoplasm of mature B-cells

Most studied deeper sub-types

Smoldering plasma cell myeloma (63) Hairy cell leukemia variant (9) Refractory hairy cell leukemia (9) Light chain deposition disease (8) Extramedullary plasmacytoma (7) Grade III lymphomatoid granulomatosis (4) Solitary osseous plasmacytoma (4) EZB-MYC+ diffuse large B-cell lymphoma (2) Heavy chain deposition disease (2) Pregerminal center chronic lymphocytic leukemia/small lymphocytic lymphoma (2) Primary plasmacytoma of the bone (2) Alpha-heavy chain disease (1) Indolent plasma cell myeloma (1) Non-secretory plasma cell myeloma (1) Central nervous system anaplastic large cell lymphoma (0) Chronic lymphocytic leukemia/small lymphocytic lymphoma with immunoglobulin heavy chain variable-region gene somatic hypermutation (0) Delta-heavy chain disease (0) Epsilon-heavy chain disease (0) Extramedullary soft tissue plasmacytoma (0) EZB-MYC- diffuse large B-cell lymphoma (0)
Including sub-types (4517) Tagged with Neoplasm of mature B-cells (14)
Trials to join now! 4 Not yet recruiting 4 Not yet finished but already full! 2 Completed 4
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