Narcolepsy-cataplexy syndrome
MONDO:0016158A type of narcolepsy characterized by excessive day-time sleepiness associated with uncontrollable sleep urges and cataplexy (loss of muscle tone often triggered by pleasant emotions).
Also known as: Gelineau disease, Gelineau syndrome, Gelineau's syndrome, Gélineau disease, narcolepsy type 1, narcolepsy with cataplexy, narcolepsy-cataplexy syndrome, narcoleptic syndrome
58 clinical trials for this condition and its sub-types.
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Narcolepsy drug trial halted early: what happened?
Symptom relief TerminatedThis early-stage study tested an experimental drug called MK-6552 in 9 people with narcolepsy type 1, a condition that causes sudden sleep attacks. The goal was to see if the drug was safe and could help patients stay awake during the day. The trial was stopped early, so results …
Phase: PHASE1 • Sponsor: Merck Sharp & Dohme LLC • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC
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New narcolepsy drug tested in tiny trial – but study halted early
Symptom relief TerminatedThis early-stage trial tested an experimental drug called JZP441 in just 6 adults with narcolepsy type 1, a condition that causes sudden daytime sleepiness. The goal was to see if the drug could help people stay awake longer, as measured by a standard sleep test. However, the stu…
Phase: PHASE1 • Sponsor: Jazz Pharmaceuticals • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC