New narcolepsy drug tested in tiny trial – but study halted early

NCT ID NCT06961266

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tested an experimental drug called JZP441 in just 6 adults with narcolepsy type 1, a condition that causes sudden daytime sleepiness. The goal was to see if the drug could help people stay awake longer, as measured by a standard sleep test. However, the study was terminated early, so we have limited information on how well it worked or its safety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

JZP441 (an oral drug)

What this could lead to

If it works, this could point toward a new treatment to help people with narcolepsy stay awake during the day.

What could go wrong

This is a very early, tiny trial (only 6 people) that was terminated, so results are limited. The drug may not work or could have side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

narcolepsy narcolepsy-cataplexy syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Clinical Trial Site

    Atlanta, Georgia, 30328, United States

  • Clinical Trial Site

    Cincinnati, Ohio, 45245, United States

  • Clinical Trial Site

    Columbia, South Carolina, 29201, United States

  • Clinical Trial Site

    Austin, Texas, 78731, United States