Myeloid leukemia
MONDO:0004643A clonal proliferation of myeloid cells and their precursors in the bone marrow, peripheral blood, and spleen. When the proliferating cells are immature myeloid cells and myeloblasts, it is called acute myeloid leukemia. When the proliferating myeloid cells are neutrophils, it is called chronic myelogenous leukemia.
Also known as: leukaemia granulocytic, leukaemia myeloid, leukemia granulocytic, leukemia myelogenous, leukemia myeloid, leukemia, granulocytic, malignant, myelocytic leukaemia, myelocytic leukemia
4354 clinical trials for this condition and its sub-types, 30 tagged with Myeloid leukemia itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Myeloid leukemia
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Acute myeloid leukemia 1,098 trials · 1,194 incl. sub-types
78 sub-types
- Acute leukemia of ambiguous lineage 53 trials · 145 incl. sub-types Sub-types →
- Therapy related acute myeloid leukemia and myelodysplastic syndrome 87 trials · 88 incl. sub-types Sub-types →
- Acute myeloid leukemia by FAB classification 0 trials · 60 incl. sub-types Sub-types →
- Acute myeloid leukemia with multilineage dysplasia 34 trials
- Acute myeloid leukemia with mutated NPM1 25 trials
- Inherited acute myeloid leukemia 1 trial · 25 incl. sub-types Sub-types →
- Childhood acute myeloid leukemia 24 trials
- Acute myeloid leukemia, MLL gene rearrangement 23 trials
- Acute monocytic leukemia 20 trials Sub-types →
- Acute myeloid leukemia, FLT3 internal tandem duplication 18 trials
- Acute myeloid leukemia with 11q23 abnormalities 11 trials
- Acute myeloid leukemia, inv(16)(p13.1;q22) 10 trials
- Acute myeloid leukemia, t(16;16)(p13.1;q22) 10 trials
- Acute myeloid leukemia with BCR-ABL1 7 trials
- Acute myeloid leukemia with t(8;21)(q22;q22) translocation 7 trials
- Acute myeloid leukemia, del(5q31-q32) 5 trials
- Acute myeloid leukemia, t(8;21)(q22; q22.1) 5 trials
- Core binding factor acute myeloid leukemia 5 trials
- Acute myeloid leukemia with CEBPA somatic mutations 1 trial
- Acute myeloid leukemia with t(6;9)(p23;q34) 1 trial
- Acute myeloid leukemia, FLT3 tyrosine kinase domain point mutation 1 trial
- Acute myeloid leukemia, biallelic CEBPA gene mutation 1 trial
- Acute myeloid leukemia, t(15;17)(q24;q21) 1 trial
- Acute myeloid leukemia, t(v;11q23.3) 1 trial
- Acute myeloid leukemia with CBFA2T3-GLIS2 fusion 0 trials
- Acute myeloid leukemia with FUS-ERG fusion 0 trials
- Acute myeloid leukemia with MNX1-ETV6 fusion 0 trials
- Acute myeloid leukemia with NPM1 somatic mutations 0 trials
- Acute myeloid leukemia with NPM1-MLF1 fusion 0 trials
- Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22) 0 trials
- Acute myeloid leukemia with inv3(p21;q26.2) or t(3;3)(p21;q26.2) 0 trials
- Acute myeloid leukemia with t(8;16)(p11;p13) translocation 0 trials
- Acute myeloid leukemia with t(9;11)(p22;q23) 0 trials
- Acute myeloid leukemia, CEBPA gene mutation 0 trials
- Acute myeloid leukemia, GATA1 gene mutation 0 trials
- Acute myeloid leukemia, KIT exon 17 mutation 0 trials
- Acute myeloid leukemia, KIT exon 8 mutation 0 trials
- Acute myeloid leukemia, KIT gene mutation 0 trials
- Acute myeloid leukemia, KRAS gene mutation 0 trials
- Acute myeloid leukemia, Monosomy 5 0 trials
- Acute myeloid leukemia, Monosomy 7 0 trials
- Acute myeloid leukemia, NRAS gene mutation 0 trials
- Acute myeloid leukemia, Non-KMT2A MLLT10 rearrangement positive 0 trials
- Acute myeloid leukemia, PTPN11 gene mutation 0 trials
- Acute myeloid leukemia, RUNX1 gene mutation 0 trials
- Acute myeloid leukemia, Trisomy 8 0 trials
- Acute myeloid leukemia, WT1 gene mutation 0 trials
- Acute myeloid leukemia, del(13q14-q21) 0 trials
- Acute myeloid leukemia, der12p 0 trials
- Acute myeloid leukemia, inv(16)(p13.3;q24.3) 0 trials
- Acute myeloid leukemia, inv(3)(q21.3;q26.2) 0 trials
- Acute myeloid leukemia, loss of chromosome 17p 0 trials
- Acute myeloid leukemia, monoallelic CEBPA gene mutation 0 trials
- Acute myeloid leukemia, t(10;11)(p11.2;q23) 0 trials
- Acute myeloid leukemia, t(10;11)(p12;q23) 0 trials
- Acute myeloid leukemia, t(11;15)(p15;q35) 0 trials
- Acute myeloid leukemia, t(11;17) 0 trials
- Acute myeloid leukemia, t(11;19)(q23.3;p13.3) 0 trials
- Acute myeloid leukemia, t(11;19)(q23;p13) 0 trials
- Acute myeloid leukemia, t(11;19)(q23;p13.1) 0 trials
- Acute myeloid leukemia, t(16;21)(p11;q22) 0 trials
- Acute myeloid leukemia, t(16;21)(q24;q22) 0 trials
- Acute myeloid leukemia, t(1;11)(q21;q23) 0 trials
- Acute myeloid leukemia, t(1;22) 0 trials
- Acute myeloid leukemia, t(1;22)(p13;q13) 0 trials
- Acute myeloid leukemia, t(2;12) 0 trials
- Acute myeloid leukemia, t(3;12)(q23;p12.3) 0 trials
- Acute myeloid leukemia, t(3;3)(q21.3;q26.2) 0 trials
- Acute myeloid leukemia, t(3;5)(q25;q34) 0 trials
- Acute myeloid leukemia, t(4;11)(q21;q23) 0 trials
- Acute myeloid leukemia, t(5;11)(q35;p15) 0 trials
- Acute myeloid leukemia, t(6;11)(q27;q23) 0 trials
- Acute myeloid leukemia, t(6;9)(p23;q34.1) 0 trials
- Acute myeloid leukemia, t(7;12)(q36;p13) 0 trials
- Acute myeloid leukemia, t(8;16) 0 trials
- Acute myeloid leukemia, t(9;11)(p21.3;q23.3) 0 trials
- Acute myeloid leukemia, t(9;22)(q34.1;q11.2) 0 trials
- Megakaryoblastic acute myeloid leukemia with t(1;22)(p13;q13) 0 trials
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Chronic myelogenous leukemia, BCR-ABL1 positive 211 trials · 253 incl. sub-types
3 sub-types
Most studied deeper sub-types
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Old drug, new hope: enasidenib may ease anemia in blood cancer patients
Disease control CompletedThis early-phase trial tested the drug enasidenib in 17 people with low-risk myelodysplastic syndrome or a related leukemia who had anemia and did not have a specific gene mutation. The goal was to see if the drug could safely improve red blood cell counts and reduce the need for…
Phase 1/2 • Sponsor: Tian Yi Zhang • Aim: Disease control
Last updated Sep 05, 2026 00:00 UTC
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New combo pill shows promise for stubborn leukemia
Disease control CompletedThis phase 2 trial tested whether adding asciminib to the standard drug imatinib helps people with chronic myeloid leukemia (CML) achieve deeper remission. 104 adults who had been on imatinib for at least a year without reaching very low cancer levels were randomly assigned to ad…
Phase 2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New dosing study aims to tame Drug-Resistant leukemia
Disease control CompletedThis study tested three different starting doses (45 mg, 30 mg, and 15 mg daily) of the drug ponatinib in 283 adults with chronic phase chronic myeloid leukemia (CML) that had stopped responding to other treatments or had a specific genetic mutation (T315I). The main goal was to …
Phase 2 • Sponsor: Takeda • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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New Two-Step transplant shows promise for tough blood cancers
Disease control CompletedThis study tested a two-step stem cell transplant for people with high-risk blood cancers like leukemia and lymphoma. First, patients got low-dose chemotherapy and radiation to prepare the body. Then, they received donor stem cells and immune cells to help destroy remaining cance…
Phase 2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Real-World data reveals how bosutinib fights leukemia outside clinical trials
Knowledge-focused CompletedThis study looks back at medical records from a single hospital in Scotland to see how well the drug bosutinib works and how safe it is for people with chronic myeloid leukemia (CML) in everyday practice. Researchers will track blood cell counts, genetic responses, and side effec…
Sponsor: Pfizer • Aim: Knowledge-focused
Last updated Jul 01, 2026 00:00 UTC
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Could natural immune cells help fight leukemia drug resistance?
Knowledge-focused CompletedThis completed study from France examined whether a specific type of immune cell (innate CD8+ T cells) is linked to how quickly resistance mutations develop in patients with chronic myeloid leukemia or Philadelphia-positive acute lymphoblastic leukemia. Researchers analyzed blood…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC