Muckle-Wells syndrome
MONDO:0008633An intermediate form of cryopyrin-associated periodic syndrome (CAPS) and is characterized by recurrent fever (with malaise and chills), recurrent urticaria-like skin rash, sensorineural deafness, general signs of inflammation (eye redness, headaches, arthralgia/myalgia) and potentially life-threatening secondary amyloidosis (AA type).
Also known as: Muckle-Wells syndrome, neutrophilic urticaria, Cryopyrin-associated periodic syndrome 2, MUCKLE-Wells syndrome, MWS, Muckle Wells syndrome, Uda syndrome, urticaria, deafness and amyloidosis
15 clinical trials for this condition and its sub-types.
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New blood markers may speed up diagnosis of childhood arthritis and fevers
Diagnosis Not yet recruitingThis study looks at two substances in the blood, IL-18 and IL-18BP, to see if they can help doctors tell apart different causes of fever in children. Researchers will measure these levels in 9 children with conditions like juvenile arthritis, autoinflammatory diseases, or serious…
Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna • Aim: Diagnosis
Last updated Jun 27, 2026 11:01 UTC
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New blood tests aim to unlock mysteries of rare inflammatory diseases
Knowledge-focused Not yet recruitingThis study aims to better understand rare autoinflammatory diseases by developing blood tests that measure inflammation markers. Researchers will analyze blood samples from 60 adults and children with these conditions. The goal is to identify specific inflammation pathways, which…
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:44 UTC