Monoclonal mast cell activation syndrome
MONDO:0033954Mast cell activation syndrome where KIT-mutated and clonal mast cells are detected.
Also known as: primary MCAS, primary mast cell activation syndrome
2 clinical trials for this condition and its sub-types.
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New study screens for hidden genetic marker in mysterious mast cell disorders
Knowledge-focused Recruiting nowThis study aims to find how common the KIT D816V mutation is in people with suspected clonal mast cell disease. Researchers will collect blood samples from 450 participants and test them using two sensitive methods. The results may improve understanding and diagnosis of these rar…
Sponsor: Blueprint Medicines Corporation • Aim: Knowledge-focused
Last updated Aug 14, 2026 00:00 UTC
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Massive study seeks genetic roots of allergies and immune problems
Knowledge-focused Recruiting nowThis study aims to find the genetic causes behind certain allergic and immune system disorders. Researchers will collect blood, saliva, and tissue samples from up to 10,000 people of all ages, along with some family members. No treatments are given; the goal is simply to learn mo…
Sponsor: Columbia University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC