Microtia
MONDO:0010920A congenital malformation of the external ear, seen more frequently in males, that occurs sporadically or is inherited, that is characterized by unilateral (79-93% of cases, 60% of which involve the right ear) or bilateral small and abnormally shaped auricles and that is often associated with atresia or stenosis of the ear canal, attention deficit disorders and delayed language development. The variation in auricle size ranges from grade I, where the auricle is simply smaller than normal, to grade IV, also known as anotia, where there is a complete absence of the external ear and of the auditory canal.
Also known as: M-A, congenital microtias, microtia, congenital, microtia-anotia, microtias, congenital, anotia
11 clinical trials for this condition and its sub-types.
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Broader categories
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Custom-grown ear implant tracked for long-term safety and looks
Disease control TerminatedThis study followed one person with microtia (a small or missing outer ear) who had already received an AUR-201 implant — a 3D-printed ear made from their own cartilage cells. Researchers checked how well the implant kept its shape and whether any side effects appeared up to 96 w…
Phase: PHASE1, PHASE2 • Sponsor: Auregen Biotherapeutics, SA • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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3D-Printed ear implant made from your own cells tested in tiny trial
Disease control TerminatedThis trial tested a new ear implant called AUR-201 for people with a rare birth defect called microtia, where one ear is small or missing. The implant was custom-made using the patient's own cartilage cells and a 3D-printed scaffold. Only 3 people were enrolled before the study w…
Phase: PHASE1, PHASE2 • Sponsor: Auregen Biotherapeutics, SA • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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Experimental ear implant tested in tiny study
Disease control TerminatedThis study tested an experimental implant called AUR-201 to rebuild the outer ear in people with unilateral microtia (one ear that is small or missing). Only 2 people enrolled before the study was stopped early. The goal was to check safety and see if the implant improved ear app…
Phase: PHASE1 • Sponsor: Auregen Biotherapeutics, SA • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC