Methanol poisoning
MONDO:0017860Methanol poisoning is a rare poisoning resulting in elevated anion gap metabolic acidosis, due to the alcohol dehydrogenase (ADH)-mediated production of formic acid (which is poisonous to the central nervous system), and characterized by dizziness, nausea, vomiting, confusion, metabolic acidosis, visual disturbances (which if left untreated can lead to blindness), coma, and death (due to respiratory failure).
4 clinical trials for this condition and its sub-types.
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Massive study tests Blood-Cleaning therapy for poisoning victims
Disease control OngoingThis study looks at whether blood-filtering treatments, such as dialysis or plasma exchange, can help people survive acute poisoning. Researchers will compare over 5,000 poisoned patients who received these treatments with those who did not. The goal is to see if the treatments i…
Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC
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Breathing device for poisoning treatment study pulled
Knowledge-focused TerminatedThis study was designed to see if a special breathing technique called isocapnic hyperventilation could help remove methanol from the blood of poisoned patients, similar to dialysis. Researchers planned to give the antidote fomepizole and use a breathing device while measuring me…
Phase: PHASE1 • Sponsor: Oslo University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC