Malignant hyperthermia of anesthesia
MONDO:0018493A pharmacogenetic disorder of skeletal muscle that presents as a hypermetabolic response to potent volatile anesthetic gasses such as halothane, sevoflurane, desflurane and the depolarizing muscle relaxant succinylcholine, and rarely, to stresses such as vigorous exercise and heat.
Also known as: anaesthesia related hyperthermia, hyperthermia of anaesthesia, hyperthermia of anesthesia, malignant hyperpyrexia, malignant hyperpyrexia due to anaesthesia, malignant hyperthermia, malignant hyperthermia of anesthesia, malignant hyperthermia syndrome
6 clinical trials for this condition and its sub-types.
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Forehead thermometer tested for kids under anesthesia
Diagnosis CompletedThis study tested whether a special forehead thermometer called SpotOn can accurately measure core body temperature in children during surgery. Researchers enrolled 70 children aged 1 day to 16 years having elective surgery. The goal was to see if this non-invasive sensor could r…
Phase: NA • Sponsor: Universitair Ziekenhuis Brussel • Aim: Diagnosis
Last updated Jun 27, 2026 07:58 UTC
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Anesthesia showdown: which drug is kinder to the optic nerve?
Knowledge-focused CompletedThis completed Phase 4 trial looked at how two common anesthetics—desflurane and propofol—affect the optic nerve sheath diameter (a measure of pressure around the eye) in 146 adults undergoing laparoscopic gallbladder removal. The goal was simply to observe differences between th…
Phase: PHASE4 • Sponsor: All India Institute of Medical Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Brain wave study reveals aging effects under anesthesia
Knowledge-focused CompletedThis completed study looked at how brain wave patterns change with age during desflurane anesthesia. Researchers recorded brain activity from 47 adults and elderly patients undergoing surgery. They analyzed different brain wave features to understand how aging affects the brain's…
Sponsor: Chinese PLA General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC