Malignant hyperthermia of anesthesia
MONDO:0018493A pharmacogenetic disorder of skeletal muscle that presents as a hypermetabolic response to potent volatile anesthetic gasses such as halothane, sevoflurane, desflurane and the depolarizing muscle relaxant succinylcholine, and rarely, to stresses such as vigorous exercise and heat.
Also known as: anaesthesia related hyperthermia, hyperthermia of anaesthesia, hyperthermia of anesthesia, malignant hyperpyrexia, malignant hyperpyrexia due to anaesthesia, malignant hyperthermia, malignant hyperthermia of anesthesia, malignant hyperthermia syndrome
6 clinical trials for this condition and its sub-types.
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Gene therapy readiness check: new study maps virus immunity in muscle disease patients
Knowledge-focused Not yet recruitingThis study will test blood samples from 450 people aged 6 to 60 with inherited neuromuscular diseases to see if they have antibodies that could block gene therapy viruses (AAVs). The goal is to understand how common these antibodies are and which patients might be good candidates…
Phase: NA • Sponsor: Genethon • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Scientists compare Anesthetics' hidden effects on metabolism
Knowledge-focused Not yet recruitingThis study looks at how two different anesthetics, sevoflurane and desflurane, change the body's metabolism during gallbladder surgery. Researchers will measure small molecules in the blood to see which metabolic pathways are affected. The goal is to understand the differences be…
Phase: NA • Sponsor: Harran University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC