Malignant colon neoplasm
MONDO:0021063A primary or metastatic malignant neoplasm that affects the colon. Representative examples include carcinoma, lymphoma, and sarcoma.
Also known as: cancer of colon, colon cancer, colon neoplasm, malignant, colon tumor, malignant, malignant colon neoplasm, malignant colon tumor, malignant colon tumour, malignant colonic neoplasm
3278 clinical trials for this condition and its sub-types, 62 tagged with Malignant colon neoplasm itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Malignant colon neoplasm
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Colon carcinoma 277 trials · 377 incl. sub-types
6 sub-types
- Colon adenocarcinoma 90 trials · 121 incl. sub-types Sub-types →
- Cecum carcinoma 1 trial · 43 incl. sub-types Sub-types →
- Rectosigmoid carcinoma 5 trials
- Colon carcinoma in situ 3 trials Sub-types →
- Colon small cell neuroendocrine carcinoma 0 trials
- Squamous cell carcinoma of colon 0 trials Sub-types →
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Cecum cancer 0 trials · 53 incl. sub-types
3 sub-types
- Appendix cancer 19 trials · 52 incl. sub-types Sub-types →
- Cecum carcinoma 1 trial · 43 incl. sub-types Sub-types →
- Cecum lymphoma 0 trials Sub-types →
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Metastasis from malignant tumor of colon 27 trials
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Sigmoid colon cancer 9 trials · 14 incl. sub-types
1 sub-type
- Rectosigmoid junction cancer 0 trials · 5 incl. sub-types Sub-types →
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Ascending colon cancer 9 trials · 10 incl. sub-types
1 sub-type
- Hepatic flexure cancer 1 trial
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Transverse colon cancer 2 trials
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Descending colon cancer 0 trials · 1 incl. sub-types
1 sub-type
- Splenic flexure cancer 1 trial
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Colon lymphoma 0 trials
3 sub-types
- Cecum lymphoma 0 trials Sub-types →
- Colon Burkitt lymphoma 0 trials
- Colon mucosa-associated lymphoid tissue lymphoma 0 trials
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Colon sarcoma 0 trials
2 sub-types
- Colon Kaposi sarcoma 0 trials
- Colon leiomyosarcoma 0 trials
Most studied deeper sub-types
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New hope for Hard-to-Treat colon cancer? study tests targeted drug combo
Disease control Stopped earlyThis study tested whether adding the experimental drug ompenaclid to standard chemotherapy could shrink tumors in people with advanced colorectal cancer that has a RAS gene mutation. About 76 participants were randomly assigned to receive either ompenaclid or a placebo, along wit…
Phase 2 • Sponsor: Inspirna, Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Turmeric compound tested against tough colon cancer
Disease control Stopped earlyThis early-stage study tested whether adding curcumin (a compound in turmeric) to standard chemotherapy could help patients with metastatic colon cancer that no longer responds to 5FU. The goal was to check safety and see if the combination shrinks tumors. Only 15 people were enr…
Early phase 1 • Sponsor: Baylor Research Institute • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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Targeted drug shows promise for rare genetic cancers
Disease control Stopped earlyThis study tested a drug called niraparib in 22 adults with advanced solid tumors (like breast, lung, or pancreatic cancer) that have a specific genetic change called a PALB2 mutation. The goal was to see if the drug could shrink tumors or slow cancer growth. The study was stoppe…
Phase 2 • Sponsor: Tempus AI • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Liver isolation chemo trial halted early – too few patients to draw conclusions
Disease control Stopped earlyThis early-phase trial tested a new way to deliver chemotherapy directly to liver tumors that spread from colorectal cancer. Doctors used balloon catheters to isolate the liver's blood supply and then infused oxaliplatin, along with oral capecitabine. Only 5 people took part befo…
Phase 1/2 • Sponsor: AllVascular • Aim: Disease control
Last updated Jun 26, 2026 18:20 UTC