Lymphoproliferative syndrome
MONDO:0016537A disorder characterized by proliferation of lymphocytes at various stages of differentiation. Lymphoproliferative disorders can be neoplastic (clonal, as in lymphomas and leukemias) or reactive (polyclonal, as in infectious mononucleosis).
Also known as: lymphoproliferative disorder, lymphoproliferative syndrome
137 clinical trials for this condition and its sub-types, 69 tagged with Lymphoproliferative syndrome itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Lymphoproliferative syndrome
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Castleman disease 8 trials · 18 incl. sub-types
4 sub-types
- Multicentric Castleman disease 13 trials
- Idiopathic multicentric Castleman disease 3 trials Sub-types →
- Localized Castleman disease 1 trial
- Pediatric Castleman disease 0 trials
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Autoimmune lymphoproliferative syndrome 11 trials · 12 incl. sub-types
9 sub-types
- Autoimmune lymphoproliferative syndrome type 4 3 trials
- FAS-related autoimmune lymphoproliferative syndrome 2 trials
- Autoimmune lymphoproliferative syndrome due to CTLA4 haploinsufficiency 1 trial
- Castleman-Kojima disease 0 trials
- Autoimmune lymphoproliferative syndrome type 1 0 trials
- Autoimmune lymphoproliferative syndrome type 2A 0 trials
- Autoimmune lymphoproliferative syndrome type 2B 0 trials
- Autoimmune lymphoproliferative syndrome, type III caused by mutation in PRKCD 0 trials
- Type 3 autoimmune lymphoproliferative syndrome 0 trials
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X-linked lymphoproliferative syndrome 7 trials · 11 incl. sub-types
2 sub-types
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Lymphoproliferative syndrome 1 0 trials
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Lymphoproliferative syndrome 2 0 trials
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New study tests which nerve block eases pain after lung surgery best
Symptom relief Not yet recruitingThis study compares two types of nerve blocks given before lung surgery to see which one controls pain better. Sixty adults having video-assisted lung surgery will receive either a serratus posterior superior intercostal plane block or a deep serratus anterior plane block. The ma…
Sponsor: Antalya City Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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New study aims to unravel mysteries of immune disorder complications
Knowledge-focused Not yet recruitingThis study looks back at medical records of about 60 people with primary immune deficiencies who also developed lymphoproliferative disorders (abnormal growth of immune cells). The goal is to track their health over time, including risks of death, cancer, or organ damage. By iden…
Sponsor: Central Hospital, Nancy, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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New immune clues could unlock better b-cell cancer treatments
Knowledge-focused Not yet recruitingThis study will measure two immune system markers, CD305 and CD85d, on cancer cells from 180 people newly diagnosed with B-cell blood cancers. The goal is to see how these markers relate to different cancer types and patient outcomes. No treatment is given; the study only observe…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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Massive study to uncover hidden link between blood mutations and immune disorders
Knowledge-focused Not yet recruitingThis study will follow 5,000 adults with immune system problems to see if certain blood cell mutations (called clonal hematopoiesis) are linked to their condition. Researchers will track new cases of immune-related diseases over time. No treatments or drugs are tested—this is pur…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Does an enlarged spleen change the outlook for low platelet patients?
Knowledge-focused Not yet recruitingThis study will look at 100 adults with low platelet counts to see how many have an enlarged spleen and whether that affects their symptoms, complications, or response to treatment. The goal is to better understand the role of the spleen in these blood disorders. No new treatment…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:59 UTC