Liver failure
MONDO:0100192A liver disease characterized by the liver losing or has lost all of its function.
Also known as: hepatic failure
199 clinical trials for this condition and its sub-types, 71 tagged with Liver failure itself.
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Sub-types of Liver failure
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Chronic liver failure 125 trials
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Acute liver failure 18 trials
1 sub-type
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Infantile liver failure 0 trials · 1 incl. sub-types
4 sub-types
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Experimental liver drug shows early promise but trial cut short
Disease control Stopped earlyThis early study tested a drug called VS-01 in 15 adults with acute-on-chronic liver failure (a sudden worsening of liver function) and fluid buildup in the belly. Participants received either VS-01 plus standard care or standard care alone. The trial was terminated early, so we …
Phase 2 • Sponsor: Genfit • Aim: Disease control
Last updated Jul 25, 2026 00:00 UTC
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Could a new drug combo prevent liver failure after tylenol overdose?
Disease control Stopped earlyThis study tested whether adding fomepizole to the standard treatment (N-acetylcysteine) could better protect the liver in people who took too much acetaminophen (Tylenol). The trial included 29 adults and children aged 10 and older who were at high risk for liver injury. The goa…
Phase 2 • Sponsor: Richard Dart, MD, PhD • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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Ear device aims to cut opioid use after liver transplant
Symptom relief Stopped earlyThis study tested a small device worn on the ear that uses mild electrical pulses to help control pain after a liver transplant. The goal was to see if it could reduce the need for strong painkillers like opioids. The study was stopped early and included 27 adults waiting for a l…
Sponsor: Duke University • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Liver study for cancer drug stopped early – only 2 people joined
Knowledge-focused Stopped earlyThis study looked at how moderate or severe liver problems change the amount of the cancer drug oral azacitidine in the blood. It was designed for adults with certain blood cancers. The study was stopped early after only 2 people enrolled, so the results are very limited.
Phase 1 • Sponsor: Bristol-Myers Squibb • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC