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Limited systemic sclerosis

MONDO:0016359

Limited systemic sclerosis (lSSc) (or SSc sine scleroderma) is a subset of systemic sclerosis (SSc) characterized by organ involvement in the absence of fibrosis of the skin.

Also known as: SSC without skin involvement, systemic sclerosis sine scleroderma, systemic sclerosis without skin involvement, Scleroderma, sine, progressive systemic sclerosis sine scleroderma

70 clinical trials for this condition and its sub-types.

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Broader categories

Disease (618) Autoimmune disease (283) Systemic sclerosis (235) Immune system disorder (140) Skin disorder (123) Rheumatic disorder (80) Connective tissue disorder (67) Scleroderma (45) Human disease (14) Disease by body system or component (0)

Trials to join now! 30 Not yet recruiting 7 Not yet finished but already full! 10 Completed 22 Terminated 1

Biopsy tolerance study ends early – what we know

Knowledge-focused Terminated

This study aimed to understand how well patients tolerate biopsies for autoimmune diseases and whether they feel properly informed. It planned to enroll 505 people but was terminated early. The results may help improve patient experience with these common procedures.

Sponsor: University Hospital, Brest • Aim: Knowledge-focused

Last updated Jun 28, 2026 00:00 UTC

Limited systemic sclerosis

Broader categories

Biopsy tolerance study ends early – what we know