Lichen planus
MONDO:0006572A chronic, recurrent, pruritic inflammatory disorder of unknown etiology that affects the skin and mucus membranes. It presents with rashes and papules that tend to resolve spontaneously. It may be associated with hepatitis C. Certain drugs that contain arsenic or bismuth are associated with reactions mimicking lichen planus.
Also known as: lichen ruber planus, ruber planus
48 clinical trials for this condition and its sub-types, 19 tagged with Lichen planus itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Lichen planus
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Lichen planus, oral 30 trials
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Lichen planus pigmentosus 2 trials
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Atrophic lichen planus 1 trial
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Hypertrophic lichen planus 1 trial
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Actinic lichen planus 0 trials
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Annular atrophic lichen planus 0 trials
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Annular lichen planus 0 trials
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Bullous lichen planus 0 trials
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Lichen planus pemphigoides 0 trials
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Lichen planus, familial 0 trials
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Linear lichen planus 0 trials
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New hope for chronic mouth condition: baricitinib trial launches
Disease control OngoingThis study tests whether baricitinib, a drug used for arthritis, can help people with moderate to severe oral lichen planus—a painful mouth condition. Ten adults who haven't improved with other treatments will take the drug for six months. Researchers will measure changes in mout…
Phase 2 • Sponsor: University of North Carolina, Chapel Hill • Aim: Disease control
Last updated Sep 03, 2026 00:00 UTC
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Glow-in-the-Dark mouth scans could catch cancer early
Diagnosis OngoingThis study tests whether special lights and cameras can help find early signs of mouth cancer in people at high risk. About 338 participants with precancerous spots or conditions like Fanconi anemia will have their mouths examined with fluorescence imaging, which makes abnormal c…
Sponsor: M.D. Anderson Cancer Center • Aim: Diagnosis
Last updated Sep 16, 2026 00:00 UTC
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Scientists hunt for clues to why lichen planus treatment fails
Knowledge-focused OngoingThis study follows 110 adults with lichen planus who are using topical steroids, the standard first treatment. Researchers will collect clinical details, saliva, blood, and tissue samples to identify factors linked to poor response. The goal is to understand why some patients don…
Sponsor: University of Aberdeen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Scratching the surface: study explores skin Irritation's role in psoriasis
Knowledge-focused CancelledThis study aimed to understand why psoriasis and lichen planus often appear on skin that is rubbed or irritated, like from tight clothing. Researchers planned to irritate a small patch of skin in people with these conditions and healthy volunteers, then take skin samples to study…
Sponsor: Marie-Charlotte Brüggen • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC