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Leukocyte adhesion deficiency

MONDO:0017570

Leukocyte adhesion deficiency (LAD) is a primary immunodeficiency characterized by defects in the leukocyte adhesion process, marked leukocytosis and recurrent infections.

Also known as: LAD

7 clinical trials for this condition and its sub-types.

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Sub-types

Leukocyte adhesion deficiency 1 (7) Leukocyte adhesion deficiency type II (2) Leukocyte adhesion deficiency 3 (0)

Broader categories

Disease (680) Hereditary disease (176) Hematologic disorder (170) Immune system disorder (148) Human disease (14) Leukocyte disorder (6) Autosomal recessive disease (4) Disease of genetic or genomic mechanism (2) Autosomal genetic disease (0) Disease by body system or component (0)

Trials to join now! 6 Not yet finished but already full! 1

Gene therapy for rare immune disease shows promise in Long-Term study

Disease control Ongoing

This study follows 9 people with a rare immune disorder called LAD-I who received a one-time gene therapy that adds a working copy of the ITGB2 gene to their own blood stem cells. Researchers want to see if the treatment safely controls the disease over many years and helps patie…

Sponsor: Rocket Pharmaceuticals Inc. • Aim: Disease control

Last updated Jun 27, 2026 08:05 UTC