Gene therapy for rare immune disease shows promise in Long-Term Follow-Up

NCT ID NCT06282432

First seen Jan 06, 2026 · Last updated May 22, 2026 · Updated 21 times

Summary

This study follows 9 people with a rare immune disorder called LAD-I who previously received a one-time gene therapy. The goal is to see if the treatment remains safe and effective over time, and whether it helps them avoid needing a stem cell transplant. Researchers will track infections, hospital stays, and skin rashes to measure success.

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Contacts and locations

Locations

  • Hospital Infantil Universitario Niño Jesús

    Madrid, 28009, Spain

  • University College London Great Ormond Street Institute of Child Health (GOSH)

    London, WC1N 1EH, United Kingdom

  • University of California, Los Angeles (UCLA)

    Los Angeles, California, 90095-1489, United States

Conditions

Explore the condition pages connected to this study.