Lentigo

This study tests whether taking an oral supplement and applying a retinol serum at night can safely reduce dark spots and brighten skin in healthy women aged 30-60. Sixty-eight Malaysian women with skin pigmentation issues like freckles or sun spots will use the products for 12 w…

This study tests two different numbing creams—one with lidocaine/prilocaine and another with lidocaine/tetracaine—against a placebo to see which works best for pain during Q-switched 532nm laser treatment for age spots (lentigines) and skin rejuvenation. Women aged 25 to 65 with …

This study tested a dark spot corrector serum along with two different skincare routines in 48 women with moderate age spots. Over 16 weeks, doctors checked if the spots got lighter, smaller, or less noticeable. The goal was to see if the treatment was safe and effective for impr…

This study followed 133 people with PPNAD (a rare adrenal gland disorder) or Carney Complex (a related genetic condition) for three years. The goal was to better understand the symptoms and genetic causes of these diseases, not to test a new treatment. Participants had yearly che…