Intrahepatic cholestasis of pregnancy
MONDO:0100429A cholestatic disorder characterized by (i) pruritus with onset in the second or third trimester of pregnancy, (ii) elevated serum aminotransferases and bile acid levels, and (iii) spontaneous relief of signs and symptoms within two to three weeks after delivery.
Also known as: gravidic intrahepatic cholestasis, intrahepatic cholestasis of pregnancy, pregnancy related cholestasis, pregnancy-related cholestasis, recurrent intrahepatic cholestasis of pregnancy, RICP, cholestasis, intrahepatic of pregnancy, familial intrahepatic cholestasis of pregnancy
19 clinical trials for this condition and its sub-types.
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Broader categories
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Special milk powder aimed to help sick infants – but study never started
Disease control TerminatedThis study planned to test whether a milk powder rich in medium-chain fatty acids could improve nutrition and health in infants with cholestatic liver disease. Researchers aimed to compare the special formula to regular milk powder in 64 infants under 6 months old. However, the s…
Phase: NA • Sponsor: Children's Hospital of Fudan University • Aim: Disease control
Last updated Jun 26, 2026 17:00 UTC
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Massive data dive aims to improve GI care
Knowledge-focused ENROLLING_BY_INVITATIONThis study is a registry that will review medical records of 1,000 patients treated for benign or malignant gastrointestinal diseases between 2005 and 2030. Researchers will look at survival, symptoms like heartburn and swallowing trouble, and quality of life. The goal is to lear…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Could bile acids cause baby lung issues? new study investigates
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at babies born to mothers with intrahepatic cholestasis of pregnancy (ICP), a liver condition that causes itching and high bile acid levels. Researchers want to see if these bile acids can lead to breathing problems in newborns. They will compare 120 babies—some …
Sponsor: Carol Davila University of Medicine and Pharmacy • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Tiny blood cells may reveal clues about liver disease in kids
Knowledge-focused OngoingThis pilot study looks at red blood cells in 20 children with cholestatic liver disease and compares them to healthy children. Researchers use a special test called ektacytometry to measure how fragile and flexible the red blood cells are. The goal is to see if liver problems cha…
Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC