Intestinal perforation
MONDO:0006807A rupture in the wall of the small or large intestine due to traumatic or pathologic processes.
Also known as: bowel perforation, perforation of intestine
13 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
-
New Stent-Suction combo shows promise for sealing gut leaks
Disease control CompletedThis study tested a device called the VAC-Stent, which combines a covered metal stent with negative pressure (suction) to seal leaks in the esophagus or colon. Researchers collected data from 110 patients to see if the device safely and effectively closed the leaks. The goal was …
Sponsor: Markus M. Heiss • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
-
Simple drug may cut infection risk after major gut surgery
Disease control CompletedThis study tested whether tranexamic acid, a drug that helps blood clot, can lower the chance of infection after gastrointestinal surgery. Over 3,300 adults at higher risk for complications took part. The goal was to see if the drug reduces surgical site infections compared to a …
Phase: PHASE4 • Sponsor: Bayside Health • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
-
New recovery plan may cut infections after emergency gut surgery
Symptom relief CompletedThis study tested whether a structured recovery plan (ERAS) could reduce infections and speed up recovery compared to standard care in 102 adults who had emergency abdominal surgery for a blocked or perforated bowel. Participants were randomly assigned to receive either the ERAS …
Phase: NA • Sponsor: Recep Tayyip Erdogan Hospital Pakistan - Muzaffargarh • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
-
Can an online wellness program ease anxiety in chronic disease?
Symptom relief CompletedThis study tested a 12-week online mind-body program for adults with chronic conditions like heart failure, cancer, and liver disease. The program included mindful movement, meditation, breathwork, and coping skills. Researchers measured changes in anxiety, depression, fatigue, a…
Phase: NA • Sponsor: University of Alberta • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
-
New study aims to spot which newborns will get worse from deadly gut disease
Knowledge-focused CompletedThis study looked back at the medical records of 400 newborns with necrotizing enterocolitis (NEC), a serious gut disease. Researchers wanted to see if combining blood test results and organ function scores could better predict which babies would develop a hole in their bowel or …
Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
-
2500 patient records analyzed to find best treatment for belly emergencies
Knowledge-focused CompletedThis study looked at the records of 2500 adults admitted to the hospital with serious belly problems like blockages or infections. The goal was to compare outcomes for different treatments, including surgery, keyhole surgery, radiology procedures, and comfort care. By grouping pa…
Sponsor: Portsmouth Hospitals NHS Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
-
Avoiding the knife: study tests Non-Surgical care for colonoscopy injuries
Knowledge-focused CompletedThis study reviewed records of 32 adults who had a colon tear during a colonoscopy to see if non-surgical care is safe and effective. Researchers looked at survival, complications, hospital stay length, and whether surgery was needed later. The goal is to find out if some patient…
Sponsor: Pirogov Russian National Research Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC