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Ichthyosis, X-linked, without steroid sulfatase deficiency

MONDO:0010223

Also known as: ichthyosis, X-linked, without steroid sulfatase deficiency

3 clinical trials for this condition and its sub-types.

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Broader categories

Disease (680) Metabolic disease (233) Inherited lipid metabolism disorder (189) Hereditary disease (176) Skin disorder (132) Inborn errors of metabolism (45) X-linked disease (16) Human disease (14) Ichthyosis (12) Hereditary skin disorder (6)

Not yet finished but already full! 1 Completed 1 Terminated 1

New ointment shows promise for rare skin condition

Disease control Completed

This Phase 3 study tested an ointment called TMB-001 in 153 people aged 6 and older with X-linked or ARCI ichthyosis, conditions that cause dry, scaly, and cracked skin. Participants applied the ointment or a placebo daily for 12 weeks, with some continuing for maintenance. The g…

Phase: PHASE3 • Sponsor: LEO Pharma • Aim: Disease control

Last updated Jun 27, 2026 12:36 UTC