Ichthyosis hystrix of Curth-Macklin
MONDO:0007808Ichthyosis hystrix of Curth-Macklin (IHCM) is a rare type of keratinopathic ichthyosis that is characterized by the presence of severe hyperkeratotic lesions and palmoplantar keratoderma (PPK).
Also known as: Curth-Macklin type ichthyosis hystrix, IHCM, Ichthyosis Hystrix, Curth Macklin Type, ichthyosis HYSTRIX, Curth-Macklin type, ichthyosis histrix, curth-macklin type, ichthyosis hystrix, Curth Macklin type, ichthyosis hystrix, Curth-Macklin type
10 clinical trials for this condition and its sub-types.
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New ointment shows promise for rare skin condition
Disease control CompletedThis Phase 3 study tested an ointment called TMB-001 in 153 people aged 6 and older with X-linked or ARCI ichthyosis, conditions that cause dry, scaly, and cracked skin. Participants applied the ointment or a placebo daily for 12 weeks, with some continuing for maintenance. The g…
Phase: PHASE3 • Sponsor: LEO Pharma • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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AI could cut skin specialist wait times, study hints
Knowledge-focused CompletedThis study tested an artificial intelligence algorithm designed to help primary care doctors decide whether a patient with a skin condition really needs to see a dermatologist. Researchers enrolled 200 adults with skin problems and had their doctors take photos of the affected ar…
Sponsor: AI Labs Group S.L • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC