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Ichthyosis, annular epidermolytic 1

MONDO:0100303

Any annular epidermolytic ichthiosis in which the cause of the disease is a variation in the KRT10 gene.

3 clinical trials for this condition and its sub-types.

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Broader categories

Disease (680) Hereditary disease (176) Skin disorder (132) Human disease (14) Ichthyosis (12) Hereditary skin disorder (6) Inherited ichthyosis (6) Disease of genetic or genomic mechanism (2) Epidermolytic ichthyosis (1) Keratinization disease (1)

Not yet finished but already full! 1 Completed 1 Terminated 1

New ointment shows promise for rare skin condition

Disease control Completed

This Phase 3 study tested an ointment called TMB-001 in 153 people aged 6 and older with X-linked or ARCI ichthyosis, conditions that cause dry, scaly, and cracked skin. Participants applied the ointment or a placebo daily for 12 weeks, with some continuing for maintenance. The g…

Phase: PHASE3 • Sponsor: LEO Pharma • Aim: Disease control

Last updated Jun 27, 2026 12:36 UTC