Hypouricemia, renal

This study tests whether adding dapagliflozin (a diabetes drug) to standard care reduces protein leakage in the urine of children with hereditary kidney diseases. About 44 children will receive either dapagliflozin plus standard care or standard care alone for 12 weeks, then swit…

This study tests an experimental drug called IG3018 for people with high uric acid, some of whom also have chronic kidney disease. About 60 adults will receive either the drug or a placebo for 4 weeks. Researchers will check safety, side effects, and how well the drug lowers uric…

This study aims to learn more about rare disorders that affect how the body processes chemicals called pyrimidines and purines. These disorders can cause problems in the brain, blood, kidneys, and immune system, ranging from mild to life-threatening. Researchers will compare test…