Hypertrophic pyloric stenosis
MONDO:0001560An abnormality characterized by thickening of the muscle in the wall of the pylorus. It results in the narrowing of the pyloric channel. The overlying mucosa may appear hypertrophic as well. Clinical signs and symptoms appear early in life and include projectile vomiting and dehydration.
Also known as: IHPS, congenital Hypertrophy of the pylorus, congenital constriction of the pylorus, congenital hypertrophic pyloric stenosis, congenital pyloric stenosis, congenital stricture of the pylorus, infantile Hypertrophy of the pylorus, infantile constriction of the pylorus
21 clinical trials for this condition and its sub-types.
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Broader categories
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New drug shows promise in early trial for kids with deadly brain cancer
Disease control CompletedThis early-phase study tested an experimental drug called INCB7839 in 13 children whose high-grade gliomas (aggressive brain tumors) had come back or worsened after standard treatment. The main goals were to find a safe dose and check for side effects. The drug works by blocking …
Phase: PHASE1 • Sponsor: Pediatric Brain Tumor Consortium • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Simple drug may cut infection risk after major gut surgery
Disease control CompletedThis study tested whether tranexamic acid, a drug that helps blood clot, can lower the chance of infection after gastrointestinal surgery. Over 3,300 adults at higher risk for complications took part. The goal was to see if the drug reduces surgical site infections compared to a …
Phase: PHASE4 • Sponsor: Bayside Health • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Can an online wellness program ease anxiety in chronic disease?
Symptom relief CompletedThis study tested a 12-week online mind-body program for adults with chronic conditions like heart failure, cancer, and liver disease. The program included mindful movement, meditation, breathwork, and coping skills. Researchers measured changes in anxiety, depression, fatigue, a…
Phase: NA • Sponsor: University of Alberta • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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Does a stomach tube prevent breathing problems in babies with pyloric stenosis?
Knowledge-focused CompletedThis study looks at whether placing a tube through the nose into the stomach (nasogastric tube) before surgery helps prevent breathing complications in infants with hypertrophic pyloric stenosis. The condition causes a blockage in the stomach outlet, leading to forceful vomiting.…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC