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Huntington disease-like 1

MONDO:0011299

Any neurodegenerative disease with chorea in which the cause of the disease is a mutation in the PRNP gene.

Also known as: HDL1, HLN1, Huntington disease-like 1, Huntington disease-like type 1, Huntington-like neurodegenerative disorder 1, PRNP neurodegenerative disease with chorea, early-onset prion disease with prominent psychiatric features, neurodegenerative disease with chorea caused by mutation in PRNP

1 clinical trial for this condition and its sub-types.

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Broader categories

Disease (680) Infectious disease (282) Nervous system disorder (231) Hereditary disease (176) Neurodegenerative disease (171) Brain disorder (125) Central nervous system disorder (107) Human disease (14) Central nervous system infectious disorder (10) Inherited neurodegenerative disorder (10)
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  • Scientists hunt for clues to predict rare brain disease before symptoms strike

    Knowledge-focused Recruiting now

    This study aims to find biological markers in spinal fluid and blood that could signal the start of prion disease before symptoms appear. Researchers will follow 150 people who carry a genetic mutation for prion disease, along with family members and healthy volunteers. Participa…

    Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused

    Last updated Aug 15, 2026 00:00 UTC

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