Hereditary neuropathy with liability to pressure palsies
MONDO:0008087Hereditary neuropathy with liability to pressure palsies (HNPP) is an inherited peripheral nerve disorder characterized by recurrent mononeuropathy usually triggered by minor physical activities.
Also known as: HNPP, Tomaculous neuropathy, current pressure-sensitive neuropathy, hereditary liability to pressure palsies, hereditary neuropathy with liability to pressure palsies, heterozygous microdeletion 17p11.2p12, neuropathy, recurrent, with pressure palsies, potato-grubbing palsy
12 clinical trials for this condition and its sub-types.
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Could a common nerve drug replace carpal tunnel surgery?
Symptom relief Not yet recruitingThis study tests whether 4-aminopyridine, a drug already approved for other nerve conditions, can improve symptoms of carpal tunnel syndrome or delay the need for surgery. Researchers will give 160 adults either the drug or a placebo for 6 weeks and track symptom changes using ha…
Phase: PHASE2 • Sponsor: John Elfar • Aim: Symptom relief
Last updated Jun 27, 2026 08:14 UTC
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Gene therapy readiness check: new study maps virus immunity in muscle disease patients
Knowledge-focused Not yet recruitingThis study will test blood samples from 450 people aged 6 to 60 with inherited neuromuscular diseases to see if they have antibodies that could block gene therapy viruses (AAVs). The goal is to understand how common these antibodies are and which patients might be good candidates…
Phase: NA • Sponsor: Genethon • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC