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Hereditary breast carcinoma
MONDO:0016419Breast carcinoma that has developed in relatives of patients with history of breast carcinoma.
Also known as: breast cancer susceptibility, autosomal dominant, somatic mutation, breast cancer, early-onset, susceptibility to, autosomal dominant, somatic mutation, breast cancer, invasive ductal, autosomal dominant, somatic mutation, breast cancer, lobular, somatic, breast cancer, male, susceptibility to, autosomal dominant, somatic mutation, breast cancer, protection against, autosomal dominant, somatic mutation, breast cancer, somatic, breast cancer, susceptibility to, autosomal dominant, somatic mutation
2814 clinical trials for this condition and its sub-types, 10 tagged with Hereditary breast carcinoma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Hereditary breast carcinoma
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New drug combo targets BRCA cancers in early trial
Disease control OngoingThis early-phase study tests a combination of two drugs, niraparib and dostarlimab, in 18 adults with BRCA-mutated breast, pancreas, or ovary cancer that has spread or cannot be surgically removed. Niraparib blocks a DNA repair protein in cancer cells, while dostarlimab helps the…
Phase 1 • Sponsor: University of Washington • Aim: Disease control
Last updated Aug 22, 2026 00:00 UTC
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Triple threat: new combo aims to tackle breast cancer brain metastases
Disease control OngoingThis study tests a three-part approach for people with breast cancer that has spread to the brain. First, they receive focused radiation (stereotactic radiosurgery) along with a drug called olaparib, which may make cancer cells more sensitive to radiation. After that, they get an…
Phase 1/2 • Sponsor: Colette Shen • Aim: Disease control
Last updated Jul 12, 2026 00:00 UTC
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Weight loss program aims to cut cancer risk in BRCA and lynch syndrome carriers
Disease control OngoingThis study tests a weight management and health behavior program for people with BRCA or Lynch syndrome mutations, who have a higher risk of certain cancers. Participants receive diet tracking, exercise guidance, phone coaching, and online support to help them lose weight and ado…
Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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Phone counseling helps latinas navigate cancer risk
Knowledge-focused OngoingThis study tests whether a culturally-informed telephone counseling program can help Latina women at high risk for hereditary breast or ovarian cancer learn more about their risk and feel more in control. About 493 women with a personal or family history of these cancers will tak…
Sponsor: City of Hope Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC