Hepatic veno-occlusive disease
MONDO:0019514Hepatic veno-occlusive disease (hepatic VOD) is a condition resulting from toxic injury to the hepatic sinusoidal capillaries that leads to obstruction of the small hepatic veins.
Also known as: Budd Chiari Syndrome, hepatic Vod, liver veno-occlusive disease, sinusoidal obstruction syndrome, veno-occlusive disease
6 clinical trials for this condition and its sub-types.
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A drug that protects the liver may make stem cell transplants safer for children with sickle cell disease
⭐️ CURE ⭐️ Recruiting nowThis trial tests whether giving defibrotide before and after a stem cell transplant can prevent a serious liver condition called sinusoidal obstructive syndrome (SOS) in children and young adults with sickle cell disease or beta thalassemia. Participants receive defibrotide start…
Phase: PHASE2 • Sponsor: New York Medical College • Aim: ⭐️ CURE ⭐️
Last updated Jul 29, 2026 00:00 UTC
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Higher defibrotide doses may help severe transplant complication
Disease control Recruiting nowThis study tests whether increasing the dose of defibrotide can safely help patients with a serious liver condition called SOS/VOD that occurs after a stem cell transplant. The condition can damage the kidneys and lungs and often does not improve with standard defibrotide doses. …
Phase: PHASE2 • Sponsor: New York Medical College • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC