Glossopharyngeal neuralgia
MONDO:0016372Glossopharyngeal neuralgia is a condition characterized by repeated episodes of severe pain in the tongue, throat, ear, and tonsils (areas connected to the ninth cranial nerve, or glossopharyngeal nerve). It typically occurs in individuals over age 40. Episodes of pain may last from a few seconds to a few minutes, and usually occur on one side. The pain may be triggered by swallowing, speaking, laughing, chewing or coughing. The condition is thought to be due to irritation of the nerve, although the source of irritation is unclear. The goal of treatment is to control pain, but over-the-counter pain medications are not very effective; the most effective drugs are anti-seizure medications. Some antidepressants help certain people. Surgery to cut or take pressure off of the glossopharyngeal nerve may be needed in severe cases.
Also known as: Glossovasopharyngeal neuralgia, glossopharyngeal nerve neuralgia, glossopharyngeal neuralgia, neuralgia of glossopharyngeal nerve
11 clinical trials for this condition and its sub-types.
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New numbing shot could ease pain after brain surgery
Symptom relief Not yet recruitingThis study tests if a long-lasting numbing drug (liposomal bupivacaine) injected into the scalp before surgery can reduce pain after a specific type of brain surgery called microvascular decompression. About 100 adults having this surgery will be randomly assigned to receive eith…
Phase: EARLY_PHASE1 • Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Global database launched to see if nerve-zapping devices really work
Knowledge-focused Not yet recruitingThis study creates a large international database to monitor how well spinal cord stimulation and similar nerve therapies work for people with chronic nerve pain. Researchers will collect real-world data from 1,000 patients across multiple countries to track safety, quality of li…
Sponsor: Poitiers University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC