Glomerulonephritis
MONDO:0002462A renal disorder characterized by damage in the glomeruli. It may be acute or chronic, focal or diffuse, and it may lead to renal failure. Causes include autoimmune disorders, infections, diabetes, and malignancies.
Also known as: glomerular nephritis, glomerulonephritis, glomerulonephritis (disease), nephritis of renal glomerulus, renal glomerulus nephritis, bright's disease
458 clinical trials for this condition and its sub-types, 33 tagged with Glomerulonephritis itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Glomerulonephritis
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Lupus nephritis 140 trials
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IgA glomerulonephritis 123 trials
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Granulomatosis with polyangiitis 95 trials · 115 incl. sub-types
1 sub-type
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Membranous glomerulonephritis 70 trials · 78 incl. sub-types
1 sub-type
- Idiopathic membranous glomerulonephritis 51 trials
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Lipoid nephrosis 32 trials
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Primary membranoproliferative glomerulonephritis 0 trials · 26 incl. sub-types
3 sub-types
- Complement 3 glomerulopathy 23 trials · 24 incl. sub-types Sub-types →
- Immunoglobulin-mediated membranoproliferative glomerulonephritis 12 trials
- Membranoproliferative glomerulonephritis, X-linked 0 trials
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Membranoproliferative glomerulonephritis 11 trials
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Pauci-immune glomerulonephritis 1 trial · 5 incl. sub-types
2 sub-types
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Rapidly progressive glomerulonephritis 3 trials · 4 incl. sub-types
1 sub-type
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Proliferative glomerulonephritis 1 trial · 2 incl. sub-types
1 sub-type
- Acute proliferative glomerulonephritis 0 trials · 1 incl. sub-types Sub-types →
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Immunotactoid glomerulopathy 1 trial
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Autoimmune glomerulonephritis 0 trials
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Diffuse glomerulonephritis 0 trials
1 sub-type
- Acute diffuse glomerulonephritis 0 trials
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Exudative glomerulonephritis 0 trials
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Focal embolic glomerulonephritis 0 trials
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Immune-complex glomerulonephritis 0 trials
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Subacute glomerulonephritis 0 trials
Most studied deeper sub-types
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Could a diabetes drug tame the immune system in kidney disease?
Disease control Not yet recruitingThis phase 2 trial tests whether dapagliflozin, a drug used for diabetes and heart failure, can reduce harmful antibodies and prevent relapses in people with membranous nephropathy, an autoimmune kidney disease. The study enrolls 20 adults who have had a recent rise in anti-PLA2R…
Phase 2 • Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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New drug BHV-1400 aims to protect kidneys in IgA nephropathy
Disease control Not yet recruitingThis Phase 3 trial tests whether BHV-1400 can safely reduce protein in the urine and preserve kidney function in 420 adults with IgA nephropathy. Participants are randomly assigned to receive either the drug or a placebo by injection. The main goal is to see if BHV-1400 lowers pr…
Phase 3 • Sponsor: Biohaven Therapeutics Ltd. • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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A simple blood test may reveal kidney damage in lupus — no biopsy needed?
Diagnosis Not yet recruitingThis study asks whether levels of uromodulin, a protein in the blood, can indicate the severity of kidney damage in people with lupus nephritis. Researchers will compare uromodulin levels with kidney biopsy results from 90 participants, including those with different classes of l…
Sponsor: Assiut University • Aim: Diagnosis
Last updated Aug 15, 2026 00:00 UTC
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Can we predict kidney Disease's return after a transplant?
Knowledge-focused Not yet recruitingThis study follows 300 adults in China who have had a kidney transplant due to glomerulonephritis (GN), a type of kidney disease. The goal is to see how often GN comes back after the transplant and what factors might influence that. Participants will be monitored for three years …
Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated Aug 27, 2026 00:00 UTC
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Computer alert aims to catch kidney disease early
Knowledge-focused Not yet recruitingThis study tests whether an electronic health record alert can help primary care doctors refer patients with blood and protein in their urine to a kidney specialist. About 1,200 adults with these high-risk signs will be included. The goal is to see if the alert improves referral …
Sponsor: Geisinger Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC