Ganglioneuroblastoma
MONDO:0005035A neuroblastic tumor characterized by the presence of neuroblastic cells, ganglion cells, and a stroma with Schwannian differentiation constituting more than fifty-percent of the tumor volume. There are two histologic subtypes identified: ganglioneuroblastoma, intermixed and ganglioneuroblastoma, nodular.
Also known as: ganglioneuroblastoma, ganglioneuroblastoma (disease), ganglioneuroblastoma (morphologic abnormality), ganglioneuroblastoma, malignant
1455 clinical trials for this condition and its sub-types, 20 tagged with Ganglioneuroblastoma itself.
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Sub-types of Ganglioneuroblastoma
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Nodular ganglioneuroblastoma 6 trials
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Peripheral ganglioneuroblastoma 0 trials
2 sub-types
- Adrenal gland ganglioneuroblastoma 0 trials
- Mediastinum ganglioneuroblastoma 0 trials
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New immunotherapy combo shows promise for tough childhood cancer
Disease control CompletedThis study tested whether adding two immunotherapy drugs (dinutuximab and GM-CSF) to standard chemotherapy is safe and doable for children newly diagnosed with high-risk neuroblastoma. Forty-two children took part. The goal was to see if the extra drugs cause too many side effect…
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New combo therapy shows promise for tough childhood cancer
Disease control CompletedThis study tested a very strong treatment plan for children newly diagnosed with high-risk neuroblastoma, a serious nerve cell cancer. The approach combined intensive chemotherapy, a radioactive drug called 131I-MIBG, and a stem cell transplant to try to kill more cancer cells. T…
Phase 1 • Sponsor: Children's Oncology Group • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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Scientists dig into tumor biology to unlock neuroblastoma secrets
Knowledge-focused CompletedThis study collects and analyzes tumor tissue from up to 10,000 children newly diagnosed with neuroblastoma or related tumors. Researchers look for biomarkers—like DNA changes and gene activity—that may help predict how the disease will behave. The goal is to better understand th…
Sponsor: Children's Oncology Group • Aim: Knowledge-focused
Last updated Jul 11, 2026 00:00 UTC