Fish eye disease
MONDO:0007620Fish eye disease (FED) is a form of genetic LCAT (lecithin-cholesterol acyltransferase) deficiency characterized clinically by corneal opacifications, and biochemically by significantly reduced HDL cholesterol and partial LCAT enzyme deficiency.
Also known as: FED, fed, fish eye disease, partial LCAT deficiency, LCATA deficiency, alpha-LCAT deficiency, alpha-lecithin cholesterol acyltransferase deficiency, alpha-lecithin:cholesterol acyltransferase deficiency
25 clinical trials for this condition and its sub-types.
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New hope for kids: drug may prevent transplant complications
Disease control Not yet recruitingThis study tests whether adding the drug vorinostat to standard care can prevent graft-versus-host disease (GVHD) in children and young adults (ages 1-26) with non-cancerous blood disorders who are getting a bone marrow transplant. GVHD is a serious complication where donor cells…
Phase: PHASE2 • Sponsor: Sung Won Choi • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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AI could help spot rare metabolic diseases in newborns
Diagnosis Not yet recruitingThis trial will test an artificial intelligence system designed to interpret routine newborn screening tests for inherited metabolic disorders. Researchers will compare the AI's accuracy to standard manual review by trained staff. The study plans to include 200,000 newborns in Ch…
Phase: NA • Sponsor: The Children's Hospital of Zhejiang University School of Medicine • Aim: Diagnosis
Last updated Jun 27, 2026 09:00 UTC
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Will breakfast change how this diabetes drug works?
Knowledge-focused Not yet recruitingThis early-stage trial in 28 healthy adults tests whether eating a meal changes how the body absorbs a single tablet containing three diabetes medicines (gemigliptin, dapagliflozin, and metformin). Participants take the pill once while fasting and once after a meal, and researche…
Phase: PHASE1 • Sponsor: LG Chem • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Massive diabetes registry aims to unlock secrets of metabolic disease
Knowledge-focused Not yet recruitingThis 10-year observational study will follow 10,000 adults with diabetes, metabolic disorders, and related conditions like high blood pressure and fatty liver disease. Researchers will collect routine medical data to identify markers of disease severity and activity. The goal is …
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC