Fetal erythroblastosis
MONDO:0006760A disorder of the fetus or newborn that occurs when fetal cells that are coated with IgG alloantibodies from the mother attack antigens inherited from the father. Severity can range from absence of symptoms to death.
Also known as: HDFN, erythroblastosis fetalis, hemolytic disease of the fetus or newborn, hemolytic disease of the foetus or newborn, hemolytic disease of the newborn, isoimmune hemolytic disease of the newborn
14 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Blood transfusion thresholds tested to save elderly surgical patients
Disease control CompletedThis study tests whether giving blood transfusions more liberally (when hemoglobin drops to 9 g/dL) versus more restrictively (when it drops to 7.5 g/dL) reduces death and serious complications like heart attack, stroke, or kidney injury in patients aged 70 and older undergoing n…
Phase: PHASE3 • Sponsor: Johann Wolfgang Goethe University Hospital • Aim: Disease control
Last updated Jul 23, 2026 00:00 UTC
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New drug shows promise for preventing severe anemia in unborn babies
Disease control CompletedThis study tested an experimental drug called M281 (nipocalimab) in 25 pregnant women at high risk for early-onset severe hemolytic disease of the fetus and newborn (HDFN), a condition where the mother's immune system attacks the baby's red blood cells. The goal was to see if the…
Phase: PHASE2 • Sponsor: Janssen Research & Development, LLC • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Anemia in kids may be tied to bigger hearts, study finds
Knowledge-focused CompletedThis study explored whether low hemoglobin (anemia) is linked to an enlarged heart (cardiomegaly) in children up to 18 years old. Researchers used chest X-rays and echocardiograms to check for heart enlargement in 56 anemic children. The goal was to better understand how anemia a…
Sponsor: Universitas Sumatera Utara • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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New study tracks High-Risk pregnancies to improve newborn health
Knowledge-focused CompletedThis study followed 17 pregnant women and their babies who were at high risk for early onset severe hemolytic disease of the fetus and newborn (EOS-HDFN). The goal was to see how the condition is currently managed and what outcomes occur. No new drugs were tested; instead, resear…
Sponsor: Janssen Research & Development, LLC • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:16 UTC